CORC

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CORC

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Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng
收藏  |  浏览/下载：76/0  |  提交时间：2022/02/14
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载：73/0  |  提交时间：2021/08/17
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X.
收藏  |  浏览/下载：102/0  |  提交时间：2020/07/01
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
CBX8 exhibits oncogenic properties and serves as a prognostic factor in hepatocellular carcinoma 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 14
作者:  Tang, Bo;  Tian, Yu;  Liao, Yong;  Li, Zeming;  Yu, Shuiping
收藏  |  浏览/下载：53/0  |  提交时间：2019/12/02
RYBP modulates stability and function of Ring1B through targeting UBE3A 期刊论文
2019, 卷号: 33, 期号: 1, 页码: 683-695
作者:  Li, Meng;  Zhang, Shiqiang;  Zhao, Wen;  Hou, Congcong;  Ma, Xiaoli
收藏  |  浏览/下载：8/0  |  提交时间：2020/01/03
Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus 期刊论文
Stem Cell Reports, 2019, 卷号: 13, 期号: 1, 页码: 115-131
作者:  Liu PP(刘佩佩);  Xu YJ(徐雅洁);  Dai SK(代尚昆);  Du HZ(杜洪震);  Wang YY(王颖颖)
收藏  |  浏览/下载：12/0  |  提交时间：2020/11/17
YY1 Positively Regulates Transcription by Targeting Promoters and Super-Enhancers through the BAF Complex in Embryonic Stem Cells 期刊论文
STEM CELL REPORTS, 2018, 卷号: 10, 期号: 4, 页码: 1324-1339
作者:  Wang, Jia;  Wu, Xingui;  Wei, Chao;  Huang, Xin;  Ma, Qian
收藏  |  浏览/下载：55/0  |  提交时间：2019/06/20
Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 302-310
作者:  Zhu, Mao-rong;  Du, Dao-hai;  Hu, Jun-chi;  Li, Lian-chun;  Liu, Jing-qiu
收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08
Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch 期刊论文
JOURNAL OF MOLECULAR BIOLOGY, 2018, 卷号: 430, 期号: 21, 页码: 4245-4259
作者:  Peng, Ling;  Wang, Longlong;  Zhang, Yingpei;  Huang, Ying;  Dong, Aiwu
收藏  |  浏览/下载：47/0  |  提交时间：2019/04/28

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