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科研机构
上海药物研究所 [16]
内容类型
期刊论文 [16]
发表日期
2020 [4]
2018 [2]
2014 [1]
2012 [1]
2011 [1]
2010 [3]
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Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 423-431
作者:
Guo, Wei
;
Yao, Sheng
;
Sun, Pu
;
Yang, Tian-biao
;
Tang, Chun-ping
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
indoleamine 2
3-dioxygenase 1 inhibitor
natural product library
high-throughput fluorescence-based screening
A new recombinant MS-superoxide dismutase alleviates 5-fluorouracil-induced intestinal mucositis in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 348-357
作者:
Yan, Xiao-xia
;
Li, Hai-long
;
Zhang, Yi-ting
;
Wu, Shou-yan
;
Lu, Heng-lei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
manganese superoxide dismutase
5-fluorouracil
chemotherapy
intestinal mucositis
diarrhea
oxidative stress
cytokines
intestinal microbes
anewrecombinantmssuperoxidedismutasealleviates5fluorouracilinducedintestinalmucositisinmice
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 348
作者:
Yan Xiaoxia
;
Li Hailong
;
Zhang Yiting
;
Wu Shouyan
;
Lu Henglei
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
manganese superoxide dismutase
5-fluorouracil
chemotherapy
intestinal mucositis
diarrhea
oxidative stress
cytokines
intestinal microbes
discoveryandcharacterizationofnaturalproductsasnovelindoleamine23dioxygenase1inhibitorsthroughhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 423
作者:
Guo Wei
;
Yao Sheng
;
Sun Pu
;
Yang Tianbiao
;
Tang Chunping
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
indoleamine 2
3-dioxygenase 1 inhibitor
natural product library
high-throughput fluorescence-based screening
Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2018
作者:
Kong, Fandi
;
Pang, Xiaoyan
;
Zhao, Jihui
;
Deng, Pan
;
Zheng, Mingyue
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/01/08
Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate
期刊论文
DRUG METABOLISM AND DISPOSITION, 2018, 卷号: 46, 期号: 9, 页码: 1320-1328
作者:
Hou, Xiangyu
;
Zhou, Jialan
;
Yu, Songda
;
Zhou, Lei
;
Zhang, Yifan
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
Discovery of a novel inhibitor of NAD(P)(+)-dependent malic enzyme (ME2) by high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 674-684
作者:
Wen, Yi
;
Xu, Lei
;
Chen, Fang-lei
;
Gao, Jing
;
Li, Jing-ya
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
malic enzyme
ME2
inhibitor
natural product
NPD389
high-throughput screening
structure-activity relationship
enzyme kinetics
thermal shift assay
High-throughput Screening and Sensitized Bacteria Identify an M. tuberculosis Dihydrofolate Reductase Inhibitor with Whole Cell Activity
期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 6
作者:
Kumar, Anuradha
;
Zhang, Meng
;
Zhu, Linyun
;
Liao, Reiling P.
;
Mutai, Charles
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Soluble Fusion Expression and Characterization of Human Beta-defensin 3 Using a Novel Approach
期刊论文
PROTEIN AND PEPTIDE LETTERS, 2011, 卷号: 18, 期号: 11, 页码: 1126-1132
作者:
Dong, Jing
;
Yu, Heguo
;
Zhang, Yonglian
;
Diao, Hua
;
Lin, Donghai
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/01/08
Expression
purification
intein
human beta-defensin3
antimicrobial activity
Emodin, a natural product, selectively inhibits 11 beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2010, 卷号: 161, 期号: 1, 页码: 113-126
作者:
Feng, Ying
;
Huang, Su-Ling
;
Dou, Wei
;
Zhang, Song
;
Chen, Jun-Hua
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
emodin
11 beta-hydroxysteroid dehydrogenase type 1
diet-induced obese mice
insulin resistance
metabolic syndrome
type 2 diabetes
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