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Wnt Signaling Pathway Collapse upon beta-Catenin Destruction by a Novel Antimicrobial Peptide SKACP003: Unveiling the Molecular Mechanism and Genetic Activities Using Breast Cancer Cell Lines
期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 3, 页码: 1
作者:
Selvarathinam, Kanitha
;
Subramani, Prabhu
;
Thekkumalai, Malarvili
;
Vilwanathan, Ravikumar
;
Selvarajan, Ramganesh
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/04/14
antimicrobial peptides
anticancer agents
breast cancer
Wnt pathway
beta-catenin
downregulation
oncology
alternative therapy
Inhibition of STAT3 Signaling Pathway by Terphenyllin Suppresses Growth and Metastasis of Gastric Cancer
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Yu, Dehua
;
Qi, Simin
;
Guan, Xiaoqing
;
Yu, Wenkai
;
Yu, Xuefei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/12/23
STAT3
inhibitor
natural product
gastric cancer
terphenyllin
Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:
Jiang, Yuchen
;
Peng, Xia
;
Ji, Yinchun
;
Dai, Yang
;
Fang, Yanfen
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  |  
浏览/下载:28/0
  |  
提交时间:2021/12/16
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
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  |  
浏览/下载:40/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Carbon ion irradiation-induced DNA damage evokes cell cycle arrest and apoptosis via the pRb/E2F1/c-Myc signaling pathway in p53-deficient prostate cancer PC-3 cells
期刊论文
NUCLEAR SCIENCE AND TECHNIQUES, 2021, 卷号: 32, 期号: 3, 页码: 12
作者:
Wang, Fang
;
Xiao, Yi
;
Yan, Jun-Fang
;
Huang, Guo-Min
;
Zhang, Jin-Hua
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/12/10
Carbon ion irradiation
DNA damage
Cell cycle arrest
Apoptosis
C-Myc
Prostate cancer
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:
Wang, Yu-xiang
;
Zhang, Xu
;
Ma, Qing-yang
;
Hu, Lan-dian
;
Zhang, Xi
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
Carbon ion irradiation-induced DNA damage evokes cell cycle arrest and apoptosis via the pRb/E2F1/c-Myc signaling pathway in p53-deficient prostate cancer PC-3 cells
期刊论文
NUCLEAR SCIENCE AND TECHNIQUES, 2021, 卷号: 32, 期号: 3
作者:
Wang, Fang
;
Xiao, Yi
;
Yan, Jun-Fang
;
Huang, Guo-Min
;
Zhang, Jin-Hua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2021/04/12
Carbon ion irradiation
DNA damage
Cell cycle arrest
Apoptosis
C-Myc
Prostate cancer
Gandou decoction, a Chinese medicinal formula, in the treatment of hepatic injury by Wnt/beta-catenin pathway regulation in models of Wilson disease
期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2020, 卷号: 9
作者:
Gao, Manli
;
Geng, Hao
;
Wu, Peng
;
Dong, Jianjian
;
Li, Hai
收藏
  |  
浏览/下载:121/0
  |  
提交时间:2020/11/30
Wilson disease (WD)
liver injury
Gandou decoction (GDD)
Wnt/beta-catenin pathway
oxidative stress
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