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Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 141
作者:  Xu, Xi;  Zhu, Xiaopeng;  Bian, Hua;  Wang, Liu;  Sun, Xiaoyang
收藏  |  浏览/下载:21/0  |  提交时间:2019/12/05
Therapeutic effects of dimethyldiguanide combined with clomifene citrate in the treatment of polycystic ovary syndrome 期刊论文
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2019, 卷号: 65, 期号: 9, 页码: 1144-1150
作者:  Jiang, Jingjing;  Gao, Shanshan;  Zhang, Yang
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression 期刊论文
LIPIDS IN HEALTH AND DISEASE, 2018, 卷号: 17
作者:  Sun, Xiaoyang;  Zhu, Xiaopeng;  Yan, Hongmei;  Xia, Mingfeng;  Chang, Xinxia
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/05
Hypolipidemic activity and mechanisms of the total phenylpropanoid glycosides from Ligustrum robustum (Roxb.) Blume by AMPK-SREBP-1c pathway in hamsters fed a high-fat diet 期刊论文
2018, 卷号: 32, 期号: 4, 页码: 715-722
作者:  Yang, Runmei;  Chu, Xinxin;  Sun, Le;  Kang, Zhuoying;  Ji, Min
收藏  |  浏览/下载:7/0  |  提交时间:2020/01/03
Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice 期刊论文
Journal of Functional Foods, 2018, 卷号: 44, 页码: 155-165
作者:  Li, Xiaopeng;  Wu, Qian;  Sui, Yong;  Li, Shuyi;  Xie, Bijun
收藏  |  浏览/下载:48/0  |  提交时间:2019/12/27
A-type procyanidins  Oxidative stress  Glucose homeostasis  Type 2 diabetes  mTOR  ACC1  acetyl coenzyme A carboxylase 1  ACL  ATP-citrate lyase  ALT  alanine aminotransferase  AST  aspartate aminotransferase  AUC  area under curve  BAT  brown adipose tissue  FAS  fatty acid synthase  FFA  free fatty acid  FoxO3a  Forkhead box O3a  FoxO1a  Forkhead box O3a  PKCβ  protein kinase C β  mTOR  mechanistic target of rapamycin  HDL  high-density lipoprotein  GHbA1c  glycated hemoglobin A1c  GK  glucokinase  G-6-Pase  glucose-6-phosphatase  GLP-1  glucagon-like peptide-1  GSH-PX  total glutathione peroxidase  HOMA-IR  homeostatic model assessment of insulin resistance  LDHA  lactate dehydrogenase  LDL  low-density lipoprotein  LPOPC  oligomeric procyanidins of litchi pericarp  MDA  malondialdehyde  MnSOD  manganese superoxide dismutase  mTOR  mechanistic target of rapamycin  OGTT  oral glucose tolerance test  PDH  pyruvate dehydrogenase  PEPCK  phosphoenolpyruvate carboxykinase  PFK  phosphofructokinase  PK  pyruvate kinase  PKCβ  protein kinase C β  PPG  postprandial blood glucose  S6K1  S6 Kinase 1  PKCβ  protein kinase C β  RTK  receptor tyrosine kinase  SREBP-1c  sterol regulatory element-binding protein 1c  ACL  ATP-citrate lyase  ACC1  acetyl coenzyme A carboxylase 1  FAS  fatty acid synthase  SCD1  stearoyl CoA desaturase 1  STZ  streptozotocin  S6K1  S6 kinase 1  PPG  postprandial blood glucose  ROS  reactive oxygen species  TC  total cholesterol  TG  triacylglycerol  STZ  streptozotocin  T-AOC  total antioxidant capacity  T-SOD  total superoxide dismutase  UCP-1  uncoupling protein 1  WAT  white adipose tissue  XOS  xylo-oligosaccharides  
Dietary cholesterol interacts with SREBF1 to modulate obesity in Chinese children 期刊论文
MOLECULAR NUTRITION & FOOD RESEARCH, 2017, 卷号: 61, 期号: 9
作者:  Zhang, Shixiu;  Lin, Xinying;  Lynn, Henry;  Xu, Guifa;  Li, Jun
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
Forkhead transcription factor 1 inhibits endometrial cancer cell proliferation via sterol regulatory element-binding protein 1 期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 13, 期号: 2, 页码: 731-737
作者:  Zhang, Yifang;  Zhang, Lili;  Sun, Hengzi;  Lv, Qingtao;  Qiu, Chunping
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/12
Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes 期刊论文
Molecular and Cellular Endocrinology, 2017, 卷号: 439, 期号: C, 页码: 155-164
作者:  Xiao, Xinhua;  Li, Han;  Qi, Xiaoyan;  Wang, Yadi;  Xu, Canxin
收藏  |  浏览/下载:19/0  |  提交时间:2019/12/27
Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity 期刊论文
JOURNAL OF HEPATOLOGY, 2014, 卷号: 61, 期号: 6, 页码: 1358-1364
作者:  Yan, Fang;  Wang, Qi;  Lu, Ming;  Chen, Wenbin;  Song, Yongfeng
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/17
NPC1, intracellular cholesterol trafficking and atherosclerosis 期刊论文
Clinica Chimica Acta, 2014, 卷号: 429, 页码: 69-75
作者:  Yu, Xiao-Hua;  Jiang, Na;  Yao, Ping-Bo;  Zheng, Xi-Long;  Cayabyab, Francisco S.
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/27
ABCA1  ATP-binding cassette transporter A1  Atherosclerosis  COX-2  Cholesterol  DHC  ER  ERK1/2  LDL  LDL-C  LDL-cholesterol  LDLR  LE/LY  LXR  N-terminal domain  NPC1  NPC2  NTD  Niemann-Pick type C1  ORP5  OSBP  OSBP-related protein 5  PPARalpha  SREBP  SSD  TGN  apoA-I  apoE  apolipoprotein A-I  apolipoprotein E  cyclooxygenase-2  dihydrocapsaicin  endoplasmic reticulum  extracellular signal-regulated kinase 1/2  late endosome/lysosome  liver X receptor  low-density lipoprotein  low-density lipoprotein receptor  oxLDL  oxidized low-density lipoprotein  oxysterol-binding protein  peroxisome proliferator-activated receptor alpha  sterol regulatory element-binding protein  sterol-sensing domain  trans-Golgi network  


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