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山东大学 [7]
南华大学 [4]
复旦大学上海医学院 [3]
武汉轻工大学 [2]
湖南中医药大学 [2]
兰州大学 [1]
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期刊论文 [21]
会议论文 [1]
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2019 [2]
2018 [3]
2017 [3]
2014 [5]
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2012 [2]
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Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 141
作者:
Xu, Xi
;
Zhu, Xiaopeng
;
Bian, Hua
;
Wang, Liu
;
Sun, Xiaoyang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Berberine
Nonalcoholic fatty liver disease
NAFLD
Stearyl-coenzyme A desaturase 1
SCD1
Sterol regulatory element-binding protein-1c
SREBP-1c
AMP-activated protein kinase
AMPK
Therapeutic effects of dimethyldiguanide combined with clomifene citrate in the treatment of polycystic ovary syndrome
期刊论文
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2019, 卷号: 65, 期号: 9, 页码: 1144-1150
作者:
Jiang, Jingjing
;
Gao, Shanshan
;
Zhang, Yang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Polycystic ovary syndrome
Clomiphene
Metformin
Sterol Regulatory
Element Binding Protein 1
Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression
期刊论文
LIPIDS IN HEALTH AND DISEASE, 2018, 卷号: 17
作者:
Sun, Xiaoyang
;
Zhu, Xiaopeng
;
Yan, Hongmei
;
Xia, Mingfeng
;
Chang, Xinxia
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Nonalcoholic fatty liver disease
NAFLD
Metformin
Stearyl-coenzyme A desaturase 1
SCD1
Adenosine monophosphate-activated protein kinase
AMPK
Sterol regulatory element-binding protein-1c
SREBP-1c
Hypolipidemic activity and mechanisms of the total phenylpropanoid glycosides from Ligustrum robustum (Roxb.) Blume by AMPK-SREBP-1c pathway in hamsters fed a high-fat diet
期刊论文
2018, 卷号: 32, 期号: 4, 页码: 715-722
作者:
Yang, Runmei
;
Chu, Xinxin
;
Sun, Le
;
Kang, Zhuoying
;
Ji, Min
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
AMP-activated protein kinase (AMPK)
hamster
hyperlipidemia
sterol regulatory element binding protein-1c (SREBP-1c)
total phenylpropanoid glycoside from Ligustrum robustum (Roxb
) Blume (LRTPG)
triglyceride
Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice
期刊论文
Journal of Functional Foods, 2018, 卷号: 44, 页码: 155-165
作者:
Li, Xiaopeng
;
Wu, Qian
;
Sui, Yong
;
Li, Shuyi
;
Xie, Bijun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/27
A-type procyanidins
Oxidative stress
Glucose homeostasis
Type 2 diabetes
mTOR
ACC1
acetyl coenzyme A carboxylase 1
ACL
ATP-citrate lyase
ALT
alanine aminotransferase
AST
aspartate aminotransferase
AUC
area under curve
BAT
brown adipose tissue
FAS
fatty acid synthase
FFA
free fatty acid
FoxO3a
Forkhead box O3a
FoxO1a
Forkhead box O3a
PKCβ
protein kinase C β
mTOR
mechanistic target of rapamycin
HDL
high-density lipoprotein
GHbA1c
glycated hemoglobin A1c
GK
glucokinase
G-6-Pase
glucose-6-phosphatase
GLP-1
glucagon-like peptide-1
GSH-PX
total glutathione peroxidase
HOMA-IR
homeostatic model assessment of insulin resistance
LDHA
lactate dehydrogenase
LDL
low-density lipoprotein
LPOPC
oligomeric procyanidins of litchi pericarp
MDA
malondialdehyde
MnSOD
manganese superoxide dismutase
mTOR
mechanistic target of rapamycin
OGTT
oral glucose tolerance test
PDH
pyruvate dehydrogenase
PEPCK
phosphoenolpyruvate carboxykinase
PFK
phosphofructokinase
PK
pyruvate kinase
PKCβ
protein kinase C β
PPG
postprandial blood glucose
S6K1
S6 Kinase 1
PKCβ
protein kinase C β
RTK
receptor tyrosine kinase
SREBP-1c
sterol regulatory element-binding protein 1c
ACL
ATP-citrate lyase
ACC1
acetyl coenzyme A carboxylase 1
FAS
fatty acid synthase
SCD1
stearoyl CoA desaturase 1
STZ
streptozotocin
S6K1
S6 kinase 1
PPG
postprandial blood glucose
ROS
reactive oxygen species
TC
total cholesterol
TG
triacylglycerol
STZ
streptozotocin
T-AOC
total antioxidant capacity
T-SOD
total superoxide dismutase
UCP-1
uncoupling protein 1
WAT
white adipose tissue
XOS
xylo-oligosaccharides
Dietary cholesterol interacts with SREBF1 to modulate obesity in Chinese children
期刊论文
MOLECULAR NUTRITION & FOOD RESEARCH, 2017, 卷号: 61, 期号: 9
作者:
Zhang, Shixiu
;
Lin, Xinying
;
Lynn, Henry
;
Xu, Guifa
;
Li, Jun
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
Childhood obesity
Dietary cholesterol
LDL-cholesterol
Nutrigenetics
Sterol regulatory element binding protein 1 gene
Forkhead transcription factor 1 inhibits endometrial cancer cell proliferation via sterol regulatory element-binding protein 1
期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 13, 期号: 2, 页码: 731-737
作者:
Zhang, Yifang
;
Zhang, Lili
;
Sun, Hengzi
;
Lv, Qingtao
;
Qiu, Chunping
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/12
Endometrial cancer
Forkhead transcription factor 1
Sterol regulatory element-binding protein 1
Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes
期刊论文
Molecular and Cellular Endocrinology, 2017, 卷号: 439, 期号: C, 页码: 155-164
作者:
Xiao, Xinhua
;
Li, Han
;
Qi, Xiaoyan
;
Wang, Yadi
;
Xu, Canxin
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/27
Non-alcoholic fatty liver disease
Triglycerides
Fatty acid oxidation
Lipogenesis
Nuclear receptors
Adiponectin
ZAG
zinc alpha2 glycoprotein
NAFLD
non-alcoholic fatty liver disease
TG
triglycerides
PA
palmitic acid
SREBP-1c
sterol-regulatory element binding protein 1c
LXR
liver X receptor
FXR
farnesoid X receptor
PPARα
peroxisome proliferator-activated receptor alpha
FAS
fatty acid synthase
ACC
acetyl-CoA carboxylase
SCD-1
stearoyl-CoA desaturase 1
FATP
fatty acid transport protein
CPT-1A
carnitine palmitoyltransferase 1A
Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity
期刊论文
JOURNAL OF HEPATOLOGY, 2014, 卷号: 61, 期号: 6, 页码: 1358-1364
作者:
Yan, Fang
;
Wang, Qi
;
Lu, Ming
;
Chen, Wenbin
;
Song, Yongfeng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
Thyrotropin (TSH)
Hepatic steatosis
Triglyceride
Sterol regulatory
element-binding protein 1c
Peroxisome proliferator-activated receptor
alpha
NPC1, intracellular cholesterol trafficking and atherosclerosis
期刊论文
Clinica Chimica Acta, 2014, 卷号: 429, 页码: 69-75
作者:
Yu, Xiao-Hua
;
Jiang, Na
;
Yao, Ping-Bo
;
Zheng, Xi-Long
;
Cayabyab, Francisco S.
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/27
ABCA1
ATP-binding cassette transporter A1
Atherosclerosis
COX-2
Cholesterol
DHC
ER
ERK1/2
LDL
LDL-C
LDL-cholesterol
LDLR
LE/LY
LXR
N-terminal domain
NPC1
NPC2
NTD
Niemann-Pick type C1
ORP5
OSBP
OSBP-related protein 5
PPARalpha
SREBP
SSD
TGN
apoA-I
apoE
apolipoprotein A-I
apolipoprotein E
cyclooxygenase-2
dihydrocapsaicin
endoplasmic reticulum
extracellular signal-regulated kinase 1/2
late endosome/lysosome
liver X receptor
low-density lipoprotein
low-density lipoprotein receptor
oxLDL
oxidized low-density lipoprotein
oxysterol-binding protein
peroxisome proliferator-activated receptor alpha
sterol regulatory element-binding protein
sterol-sensing domain
trans-Golgi network
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