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中南大学 [8]
兰州大学 [5]
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上海药物研究所 [2]
山东大学 [2]
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期刊论文 [22]
会议论文 [1]
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2019 [6]
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2012 [3]
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1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 448-456
作者:
Jiang, Junhang
;
Zhang, Hao
;
Wang, Chongqing
;
Zhang, Qingsen
;
Fang, Shaoyu
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Microtubule-targeting agents
Colchicine site inhibitors
Cis-trans photoisomerization
X-ray co-crystal structure
Water-soluble prodrug
Multi-scale Dense Networks for Deep High Dynamic Range Imaging
会议论文
2019 IEEE WINTER CONFERENCE ON APPLICATIONS OF COMPUTER VISION (WACV), 2019-01-01
作者:
Yan, Qingsen
;
Gong, Dong
;
Zhang, Pingping
;
Shi, Qinfeng
;
Sun, Jinqiu
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/02
Computer vision
Deep neural networks
Neural networks, Convolutional neural network
High dynamic range images
High dynamic range imaging
Low dynamic range
Missing information
Quantitative experiments
State-of-the-art approach
State-of-the-art methods, Image reconstruction
State-independent alterations of intrinsic brain network in current and remitted depression
期刊论文
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2019, 卷号: 89, 页码: 475-480
作者:
Dong, Daifeng
;
Ming, Qingsen
;
Zhong, Xue
;
Pu, Weidan
;
Zhang, Xiaocui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
Major depressive disorder
Remitted depression
Functional connectivity
Topologically state-independent and dependent functional connectivity patterns in current and remitted depression.
期刊论文
Journal of affective disorders, 2019, 卷号: 250, 页码: 178-185
作者:
Dong Daifeng
;
Li Chuting
;
Ming Qingsen
;
Zhong Xue
;
Zhang Xiaocui
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/03
*Current depression
*Graph theory
*Remitted depression
Synthesis and biological evaluation of 7-methoxy-1-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-benzo[e]indazoles as new colchicine site inhibitors.
期刊论文
Bioorganic and Medicinal Chemistry Letters, 2019, 卷号: 29, 期号: 18, 页码: 2632-2634
作者:
Jiang, Junhang
;
Zhang, Qingsen
;
Guo, Jiapeng
;
Fang, Shaoyu
;
Zhou, Ruolan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/27
Antitumor activity
Colchicine site inhibitors
NCI-60 human tumor cell lines screen
Tubulin polymerization inhibitors
Design, synthesis, and bioactivity evaluation of novel Bcl-2/HDAC dual-target inhibitors for the treatment of multiple myeloma.
期刊论文
Bioorganic & medicinal chemistry letters, 2019, 卷号: 29, 期号: 3, 页码: 349-352
作者:
Zhou, Ruolan
;
Fan, Shaoyu
;
Zhang, Minmin
;
Zhang, Qingsen
;
Hu, Jian
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/27
Anti-tumor agents
Bcl-2 inhibitors
Dualtarget inhibitors
HDAC inhibitors
HDAC6 inhibitors
Multiple myeloma
Design, synthesis, and bioactivity evaluation of novel Bcl-2/HDAC dual-target inhibitors for the treatment of multiple myeloma
期刊论文
Bioorganic & medicinal chemistry letters, 2018
作者:
Zhou, Ruolan
;
Fang, Shaoyu
;
Zhang, Minmin
;
Zhang, Qingsen
;
Hu, Jian
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/01/08
MAOA genotype modulates default mode network deactivation during inhibitory control
期刊论文
Biological psychology, 2018, 卷号: 138, 页码: 27-34
作者:
Ma, Ren
;
Gan, Gabriela
;
Zhang, Jibiao
;
Ming, Qingsen
;
Jiang, Yali
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
*Aggression
*Default mode network
*Inhibitory control
*MAOA gene
State-Independent and Dependent Neural Responses to Psychosocial Stress in Current and Remitted Depression.
期刊论文
The American journal of psychiatry, 2017, 卷号: 174, 期号: 10, 页码: 971-979
作者:
Ming, Qingsen
;
Zhong, Xue
;
Zhang, Xiaocui
;
Pu, Weidan
;
Dong, Daifeng
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/03
*Mood Disorders-Unipolar
*Stress
Whole-brain resting-state functional connectivity identified major depressive disorder: A multivariate pattern analysis in two independent samples
期刊论文
Journal of Affective Disorders, 2017, 卷号: 218, 页码: 346-352
作者:
Zhong, Xue
;
Shi, Huqing
;
Ming, Qingsen
;
Dong, Daifeng
;
Zhang, Xiaocui
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
MDD
major depressive disorder
fMRI
functional magnetic resonance imaging
FC
functional connectivity
DMN
default mode network
SN
salience network
CEN
central executive network
HCs
healthy controls
MVPA
multivariate pattern analysis
CES-D
epidemiologic studies depression scale
HDRS
Hamilton depression rating scale
MNI
Montreal Neurological Institute
Major depressive disorder
Multivariate pattern analysis
Resting-state fMRI
Whole-brain functional connectivity
Classification
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