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Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文
LEUKEMIA, 2022
作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng
收藏  |  浏览/下载:76/0  |  提交时间:2022/02/14
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing
收藏  |  浏览/下载:80/0  |  提交时间:2021/11/04
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:  Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya
收藏  |  浏览/下载:34/0  |  提交时间:2021/05/24
Biological roles of LSD1 beyond its demethylase activity 期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2020
作者:  Gu, Feiying;  Lin, Yuxin;  Wang, Zhun;  Wu, Xiaoxin;  Ye, Zhenyue
收藏  |  浏览/下载:19/0  |  提交时间:2020/11/26
Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers 期刊论文
2019, 卷号: 33, 期号: 8, 页码: 9672-9684
作者:  Wang, Chao;  Zhang, Bin;  Ratliff, Anna C.;  Arrington, Justine;  Chen, Jingjuan
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/03
Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 80, 页码: 649-654
作者:  Zhang, Li;  Chen, Yantao;  Liu, Na;  Li, Linjuan;  Xiao, Senhao
收藏  |  浏览/下载:38/0  |  提交时间:2019/01/08
Histone deacetylation, as opposed to promoter methylation, results in epigenetic BIM silencing and resistance to EGFR TKI in NSCLC 期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 期号: 1
作者:  Zhao, Mingchuan;  Zhang, Yishi;  Li, Jiayu;  Li, Xuefei;  Cheng, Ningning
收藏  |  浏览/下载:16/0  |  提交时间:2019/12/05
The Epigenetics of Alzheimer's Disease: Factors and Therapeutic Implications. 期刊论文
Frontiers in genetics, 2018, 页码: 579
作者:  Liu Xiaolei;  Jiao Bin;  Shen Lu
收藏  |  浏览/下载:13/0  |  提交时间:2019/02/25
The Epigenetics of Alzheimer's Disease: Factors and Therapeutic Implications. 期刊论文
Frontiers in genetics, 2018, 页码: 579
作者:  Liu Xiaolei;  Jiao Bin;  Shen Lu
收藏  |  浏览/下载:3/0  |  提交时间:2019/02/25
The Epigenetics of Alzheimer’s Disease: Factors and Therapeutic Implications 期刊论文
Frontiers in Genetics, 2018, 卷号: Vol.9
作者:  Xiaolei Liu;  Bin Jiao;  Lu Shen
收藏  |  浏览/下载:7/0  |  提交时间:2019/02/25


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