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上海药物研究所 [21]
大连化学物理研究所 [16]
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期刊论文 [78]
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浏览/检索结果:
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Molecular dynamics simulations reveal the mechanism of the interactions between the inhibitors and SIRT2 at atom level
期刊论文
MOLECULAR SIMULATION, 2020, 卷号: 46, 期号: 8, 页码: 638-649
作者:
Wang, Xiaoyu
;
Song, Menghua
;
Zhao, Shuang
;
Li, Huiyu
;
Zhao, Qingjie
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
SIRT2
inhibitor
molecular dynamics simulation
TCMs
hydrophobic and pi-pi interactions
Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 7, 页码: 15
作者:
Zhao, Shuang
;
Zhu, Yan-Yan
;
Wang, Xiao-Yu
;
Liu, Yong-Sheng
;
Sun, Yun-Xiang
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
SIRT6
inhibitor
nature molecule
molecular dynamics simulation
scutellarin
hydrophobic interactions
pi-stacking interactions
binding sites
High degree of pharmacokinetic compatibility exists between the five-herb medicine XueBiJing and antibiotics comedicated in sepsis care
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 1035-1049
作者:
Li, Jian
;
Olaleye, Olajide E.
;
Yu, Xuan
;
Jia, Weiwei
;
Yang, Junling
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
XueBiJing
Antibiotic
Combination drug therapy
Sepsis
Pharmacokinetic compatibility
Herb-drug interaction
Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312
作者:
Liu, Man
;
Xiao, Cheng-qian
;
Sun, Ming-wei
;
Tan, Min-jia
;
Hu, Li-hong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
covalent interaction
IKK inhibitor
JAK inhibitor
natural compound
Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 166, 页码: 52-65
作者:
Zhi, Haijuan
;
Deng, Yanping
;
Yan, Bingpeng
;
Li, Zhenwei
;
Han, Sumei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Danqi Tongmai tablet
Herb-herb interaction
Acute myocardial ischemic
UHPLC-TQ/MS
Pharmacokinetics
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:
Tian, Xiaoting
;
Liu, Fang
;
Li, Zhixiong
;
Lin, Yunfei
;
Liu, Huan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
berberine
timosaponin B2
diabetes
combination treatments
drug-drug interaction
metabolites
hepatic metabolism
intestinal absorption
Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 6, 页码: 1048-1063
作者:
Zhong, Chen-chun
;
Chen, Feng
;
Yang, Jun-ling
;
Jia, Wei-wei
;
Li, Li
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
anlotinib
tyrosine kinase inhibitor
absorption
distribution
metabolism
excretion
pharmacokinetics
Effects of catalpol on the activity of human liver cytochrome P450 enzymes
期刊论文
Xenobiotica, the fate of foreign compounds in biological systems, 2018, 页码: 1-19
作者:
Liu Lu[1]
;
Cao Xiangang[2]
;
Li Tingxin[3]
;
Li Xiaohua[4]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/04/22
CYP2C9
CYP2E1
CYP3A4
Catalpol
Herb-drug interaction
Effects of catalpol on the activity of human liver cytochrome P450 enzymes.
期刊论文
Xenobiotica, the fate of foreign compounds in biological systems, 2018, 页码: 1-19
作者:
Liu Lu
;
Cao Xiangang
;
Li Tingxin
;
Li Xiaohua
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/26
CYP2C9
CYP2E1
CYP3A4
Catalpol
Herb-drug
interaction
The Herb-Drug Interaction of Clopidogrel and Xuesaitong Dispersible Tablet by Modulation of the Pharmacodynamics an Liver Carboxylesterase 1A Metabolism
期刊论文
2018
作者:
Ma, Shitang
;
Dai, Guoliang
;
Bi, Xiaolin
;
Gong, Meirong
;
Miao, Chenggui
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/01/03
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