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上海生物化学与细胞生... [5]
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期刊论文 [21]
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Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 5, 页码: 836-845
作者:
Che, Jinxin
;
Wang, Zhilong
;
Shen, Zheyuan
;
Zhuang, Weihao
;
Ying, Huazhou
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
cancer metastasis
CXCR1
CXCR2
selectivity
antagonist
1,5-dihydro-4H-imidazol-4-one
Mechanism of Cxc Chemokine Ligand 5 (CXCL5)/Cxc Chemokine Receptor 2 (CXCR2) Bio-Axis in Mice with Acute Respiratory Distress Syndrome
期刊论文
MEDICAL SCIENCE MONITOR, 2019, 卷号: 25
作者:
Wang, Chang-yong
;
Shang, Min
;
Zhou, Chen-liang
;
Feng, Li-zhi
;
Zhou, Qing-shan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Chemokine CXCL5
Inflammation
Respiratory Distress Syndrome, Adult
Ligand-based pharmacophore model for the discovery of novel CXCR2 antagonists as anti-cancer metastatic agents
期刊论文
ROYAL SOCIETY OPEN SCIENCE, 2018, 卷号: 5, 期号: 7
作者:
Che, Jinxin
;
Wang, Zhilong
;
Sheng, Haichao
;
Huang, Feng
;
Dong, Xiaowu
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
pharmacophore model
CXCR2
antagonists
anti-cancer metastasis
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 149, 页码: 148-169
作者:
Peng, Dian
;
Cao, Bin
;
Zhou, Ying-Jun
;
Long, Ya-Qiu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
CXC chemokine receptor 4
Small molecule antagonists
Structure-based optimization
HIV-1 entry
Tumor metastasis
Inflammation
Ischemia-reperfusion
Autoimmune
Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 34, 页码: 8621-8626
作者:
He, Lan
;
Gu, Wangpeng
;
Zhang, Yuan
;
Yan, Chenghua
;
Su, Pan
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2019/04/28
Cxc Chemokine Receptor-5
Icos
Bcl6
Induction
Responses
Stat5
Pd-1
Fh
Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3 beta/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia
期刊论文
CIRCULATION RESEARCH, 2017, 卷号: 120, 期号: 5
作者:
Dai, Xiaozhen
;
Yan, Xiaoqing
;
Zeng, Jun
;
Chen, Jing
;
Wang, Yuehui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
angiogenesis
chemokine CXCL12
CXC chemokine receptor type 7
endothelial progenitor cells
hindlimb ischemia
High CXC chemokine receptor 1 level represents an independent negative prognosticator in non-metastatic clear-cell renal cell carcinoma patients
期刊论文
ONCOIMMUNOLOGY, 2017, 卷号: 6, 期号: 11
作者:
Zhu, Yu
;
Liu, Zheng
;
Wang, Yiwei
;
Fu, Hangcheng
;
Wang, Zewei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
clear-cell renal cell carcinoma
CXC chemokine receptor 1
overall survival
prognostic biomarker
recurrence-free survival
CXC chemokine receptor 1 predicts postoperative prognosis and chemotherapeutic benefits for TNM II and III resectable gastric cancer patients
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 12
作者:
Cao, Yifan
;
Liu, Hao
;
Zhang, Heng
;
Lin, Chao
;
Li, Ruochen
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
CXCR1
gastric cancer
nomogram
overall survival
adjuvant chemotherapy
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis
期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 92-100
作者:
Luo, Yangyang
;
Wang, Yong
;
Shu, Ye
;
Lu, Qianjin
;
Xiao, Rong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
SSc
systemic sclerosis
SRC
scleroderma renal crisis
PAH
pulmonary arterial hypertension
SMR
standardized mortality ratio
DNMTs
DNA methyltransferases
SAM
S-adenosyl-methionine
5mC
5-methylcytosine
MBD
methyl-CpG-binding domain
Tet
ten–eleven translocation
HATs
histone acetyltransferases
HDACs
histone deacetylases
MiRNAs
microRNAs
MZ
monozygotic
DZ
dizygotic
MVECs
microvascular endothelial cells
FBs
fibroblasts
JAMs
junctional adhesion molecules
CTGF
connective tissue growth facto
TGF-β
transforming growth factor beta
CCN2
connective tissue growth factor
Fli1
Friend leukemia integration-1
TF
transcription factor
PECAM
platelet/endothelial cell adhesion molecule
PDGF
platelet derived growth factor
S1P1
sphingosin 1 phosphate
CXCL5
CXC chemokine ligand-5
BMPs
bone morphogenetic proteins
BMPRII
bone morphogenetic protein type II receptor
ET-1
endotheline-1
uPA
urokinase-type plasminogen activator
MBD
methyl-CpG-binding domain protein
ICAM
intercellular adhesion molecule
KLF5
Kruppel-like factor 5
Tregs
regulatory T cells
Runx1
Runt-related transcription factor 1
FOXP3
forkhead box protein 3 gene
ECM
extra cellular matrix
PDGF
platelet-derived growth factor
dSSc
diffuse systemic sclerosis
lSSc
limited systemic sclerosis
PCAF
protein-associated factor
Egr-1
early growth response 1
DDR2
discoidin domain receptor 2
TAB1
TGF-β activated kinase 1 binding protein 1
BAFF
B cell-activating factor
TSP-2
thrombospondin-2
MRTSS
Modified Rodnan total skin score
SDAI
Valentini scleroderma disease activity index
HC
healthy controls
SLE
systemic lupus erythematosus
SSD
scleroderma spectrum disorder
MTX
methylaminopterin
CYC
cyclophosphamide
MMF
mycophenolate mofetil
ACE
angiotensin converting enzyme
NO
nitric oxide
Systemic sclerosis
Epigenetic mechanisms
Biomarker
Therapy
Effect of SDF-1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2015, 卷号: 36, 期号: 5
作者:
Li, Jun
;
Guo, Weichun
;
Xiong, Min
;
Han, Heng
;
Chen, Jie
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
stromal cell-derived factor-1/CXC chemokine receptor 4 axis
bone marrow-derived mesenchymal stem cells
erythropoietin
spinal cord injury
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