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复旦大学上海医学院 [5]
南华大学 [4]
厦门大学 [3]
上海药物研究所 [3]
中国医学科学院 北京... [3]
昆明植物研究所 [2]
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期刊论文 [31]
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Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:
Hu, Ke
;
Li, Bo
;
Ma, Ruye
;
Yi, Hongfei
;
Xu, Zhijian
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/06/11
caspase
cell proliferation
cell cycle arrest
diffuse large B-cell lymphoma
PI3K-AKT-mTOR/JNK pathway
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway
Silibinin Retards Colitis-associated Carcinogenesis by Repression of Cdc25C in Mouse Model
期刊论文
2019, 卷号: 25, 期号: 7, 页码: 1187-1195
作者:
Li, Weiwei
;
Zhao, Xinhua
;
Lv, Xue
;
Han, Wenxiao
;
Wang, Hongying
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
colitis-associated carcinogenesis
silibinin
Cdc25c
cell cycle arrest
animal model
Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 4
作者:
Wang, Yaqi
;
Yang, Lifeng
;
Zhang, Jing
;
Zhou, Menglong
;
Shen, Lijun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
irinotecan
radiosensitization
p53-mutant colorectal cancer cells
DNA damage response
cell cycle
cell apoptosis
Radiosensitization of Irinotecan is Attributed to G2/M Phase Arrest, Followed by Enhanced Apoptosis Probably Through the ATM/Chk/Cdc25C/Cdc2 Pathway in P53-mutant Colon Cancer Cells
会议论文
作者:
Wang, Y.
;
Zhang, J.
;
Yang, L.
;
Liang, L.
;
Zhang, H.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells
期刊论文
International Journal of Oncology, 2018, 卷号: Vol.53 No.4, 页码: 1667-1680
作者:
Yaqi Wang
;
Lifeng Yang
;
Jing Zhang
;
Menglong Zhou
;
Lijun Shen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/26
Sodium Fluoride Arrests Renal G2/M Phase Cell-Cycle Progression by Activating ATM-Chk2-P53/Cdc25C Signaling Pathway in Mice.
期刊论文
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, 卷号: Vol.51 No.5, 页码: 2421-2433
作者:
Luo Qin
;
Guo Hongrui
;
Kuang Ping
;
Cui Hengmin
;
Deng Huidan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/26
ATM-Chk2-p53/Cdc25C
signaling
pathway
G2/M
phase
arrest
Kidney
Mice
Proliferation
Sodium
fluoride
Preclinical activity of DCZ3301, a novel aryl-guanidino compound in the therapy of multiple myeloma
期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 15, 页码: 3690-3699
作者:
Gao, Minjie
;
Li, Bo
;
Sun, Xi
;
Zhou, Yunfei
;
Wang, Yingcong
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
Multiple Myeloma
DCZ3301
antitumor activities
synergistic cytotoxicity
Hypermethylation of AKT2 gene is associated with neural-tube defects in fetus
期刊论文
PLACENTA, 2016, 卷号: 48, 页码: 80-86
作者:
Ma, Fei Fei[1]
;
Cao, Ding Ding[2]
;
Ouyang, Shengrong[1]
;
Tang, Renqiao[3]
;
Liu, Zhuo[1]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/24
Neural tube defects
Placenta
DNA methylation
T-cell receptor
Signaling pathway
AKT2
CDC25C
Hypermethylation of AKT2 gene is associated with neural-tube defects in fetus
期刊论文
2016, 卷号: 48, 页码: 80-86
作者:
Ma, Fei Fei
;
Cao, Ding Ding
;
Ouyang, Shengrong
;
Tang, Renqiao
;
Liu, Zhuo
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
Neural tube defects
Placenta
DNA methylation
T-cell receptor
Signaling pathway
AKT2
CDC25C
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