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上海药物研究所 [16]
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期刊论文 [47]
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Quantitative Proteomics Reveals the Protective Effects of Huangqi Decoction Against Acute Cholestatic Liver Injury by Inhibiting the NF-kappa B/IL-6/STAT3 Signaling Pathway
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 2, 页码: 677-687
作者:
Wu, Jia-Sheng
;
Liu, Qian
;
Fang, Shan-Hua
;
Liu, Xing
;
Zheng, Min
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
intrahepatic cholestasis
Huangqi decoction
proteomics
NF-kappa B
IL-6
STAT3
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 1: Metabolic profiles from the liver-centric perspective
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 237, 页码: 81-91
作者:
Liu, Huan
;
Chen, Mingcang
;
Yin, Hao
;
Hu, Pei
;
Wang, Yangyang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Yin-chen-hao tang
Liver
Metabolites
Liver injury
HPLC-Q-TOF
Carbon tetrachloride
Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 2: Hepatic disposition in vivo and hepatoprotective activity in vitro
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 236, 页码: 161-172
作者:
Tian, Xiaoting
;
Liu, Huan
;
Qiao, Shida
;
Yin, Hao
;
Chen, Mingcang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Yin-Chen-Hao Tang
Hepatic disposition
Pharmacokinetics
Hepatoprotection
HepG2
Carbon tetrachloride
Basal PPAR alpha inhibits bile acid metabolism adaptation in chronic cholestatic model induced by alpha-naphthylisothiocyanate
期刊论文
TOXICOLOGY LETTERS, 2019, 卷号: 300, 页码: 31-39
作者:
Hua, Huiying
;
Dai, Manyun
;
Luo, Yishuang
;
Lin, Hante
;
Xu, Gangming
收藏
  |  
浏览/下载:120/0
  |  
提交时间:2018/12/18
PPAR alpha
FXR pathway
Alpha-naphthylisothiocyanate
Chronic cholestasis
18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-Yan
;
Cui, Shi-Chao
;
Wang, Le
;
Zhang, Yi-Ting
;
Yan, Xiao-Xia
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2019/01/08
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-yan
;
Cui, Shi-chao
;
Wang, Le
;
Zhang, Yi-ying
;
Yan, Xiao-xia
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
hepatoprotective effect
cholestatic liver injury
18 beta-glycyrrhetinic acid (18b-GA)
FXR
Sirt1
bile acid transporters
Targeted Metabolomics Reveals a Protective Role for Basal PPAR alpha in Cholestasis Induced by alpha-Naphthylisothiocyanate
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 4, 页码: 1500-1508
作者:
Dai, Manyun
;
Hua, Huiying
;
Lin, Hante
;
Xu, Gangming
;
Hu, Xiaowei
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2018/05/08
Ppar Alpha
Nf-kappa b
Stat3
Alpha-naphthylisothiocyanate
Cholestasis
Yinchenhao Decoction Ameliorates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis in Rats by Regulating Phase II Metabolic Enzymes and Transporters
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Yi, Ya-Xiong
;
Ding, Yue
;
Zhang, Yong
;
Ma, Ning-Hui
;
Shi, Feng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Yinchenhao Decoction
phase II metabolism
pharmacokinetics
cholestasis
bilirubin metabolism enzyme
metabolic transporter
Different effects of ursodeoxycholic acid on intrahepatic cholestasis in acute and recovery stages induced by alpha-naphthylisothiocyanate in mice
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 卷号: 342
作者:
Qiu, Furong
;
Zhang, Linlin
;
Su, Huizong
;
Li, Yue
;
Fan, Yujuan
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Ursodeoxycholic acid
Alpha-naphthylisothiocyanate
Intrahepatic cholestasis
Hepatotoxicity
Beneficial effect of resveratrol on -naphthyl isothiocyanate-induced cholestasis via regulation of the FXR pathway
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 1
作者:
Ding, Lili
;
Zhang, Binfeng
;
Li, Jinmei
;
Yang, Li
;
Wang, Zhengtao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
resveratrol
farnesoid X receptor
cholestasis
-naphthylisothiocyanate
inflammation
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