CORC

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CORC

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Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:  Zhou, Ting-ting;  Zhao, Tong;  Ma, Fei;  Zhang, Yi-nan;  Jiang, Jing
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
Structural insights into the potency of SK channel positive modulators 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:  Nam, Young-Woo;  Orfali, Razan;  Liu, Tingting;  Yu, Kunqian;  Cui, Meng
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway 期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169
作者:  Zhou, Ting-Ting;  Ma, Fei;  Shi, Xiao-Fan;  Xu, Xin;  Du, Te
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
SP6616 as a new Kv2.1 channel inhibitor efficiently promotes beta-cell survival involving both PKC/Erk1/2 and CaM/PI3K/Akt signaling pathways 期刊论文
CELL DEATH & DISEASE, 2016, 卷号: 7
作者:  Zhou, T. T.;  Quan, L. L.;  Chen, L. P.;  Du, T.;  Sun, K. X.
收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08
A novel target for cancer therapyeEF2K 期刊论文
Chemistry of Life, 2016, 卷号: 36, 期号: 3, 页码: 397-403
作者:  Xiao Ting;  Liu Rui;  Wang Mingwei
收藏  |  浏览/下载：9/0  |  提交时间：2019/01/08
Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKK beta-dependent AMPK activation 期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2015, 卷号: 50, 页码: 298-313
作者:  Xu, Yuan;  Xu, Yazhou;  Wang, Yurong;  Wang, Yunjie;  He, Ling
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
Increasing the sampling efficiency of protein conformational transition using velocity-scaling optimized hybrid explicit/ implicit solvent REMD simulation 期刊论文
JOURNAL OF CHEMICAL PHYSICS, 2015, 卷号: 142, 期号: 12
作者:  Yu, Yuqi;  Wang, Jinan;  Shao, Qiang;  Shi, Jiye;  Zhu, Weiliang
收藏  |  浏览/下载：7/0  |  提交时间：2019/01/08
Mapping Central alpha-Helix Linker Mediated Conformational Transition Pathway of Calmodulin via Simple Computational Approach 期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2014, 卷号: 118, 期号: 32, 页码: 9677-9685
作者:  Wang, Jinan;  Peng, Shaoliang;  Cossins, Benjamin P.;  Liao, Xiangke;  Chen, Kaixian
收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08
Exploring Transition Pathway and Free-Energy Profile of Large-Scale Protein Conformational Change by Combining Normal Mode Analysis and Umbrella Sampling Molecular Dynamics 期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2014, 卷号: 118, 期号: 1, 页码: 134-143
作者:  Wang, Jinan;  Shao, Qiang;  Xu, Zhijian;  Liu, Yingtao;  Yang, Zhuo
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
Targeting the Small- and Intermediate-Conductance Ca2+-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface 期刊论文
NEUROSIGNALS, 2014, 卷号: 22, 期号: 2, 页码: 65-78
作者:  Cui, Meng;  Qin, Guangrong;  Yu, Kunqian;  Bowers, M. Scott;  Zhang, Miao
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08

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