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科研机构
上海药物研究所 [24]
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期刊论文 [22]
会议论文 [2]
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2018 [1]
2017 [2]
2015 [1]
2013 [2]
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2010 [1]
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Pharmacolo... [1]
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The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 11, 页码: 3403-3414
作者:
Lu, Yao
;
Ma, Jiang
;
Song, Zijing
;
Ye, Yang
;
Fu, Peter P.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid
Retrorsine
ATP5B
Mitochondrial damage
Pyrrole-protein adduct
Mansouramycin C kills cancer cells through reactive oxygen species production mediated by opening of mitochondrial permeability transition pore
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 61, 页码: 104057-104071
作者:
Kuang, Shan
;
Liu, Ge
;
Cao, Ruobing
;
Zhang, Linlin
;
Yu, Qiang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
mansouramycin C
marine-derived isoquinolinequinone
reactive oxygen species
mitochondrial permeability transition pore
anticancer drug
Low molecular weight xanthan gum suppresses oxidative stress-induced apoptosis in rabbit chondrocytes
期刊论文
CARBOHYDRATE POLYMERS, 2017, 卷号: 169, 页码: 255-263
作者:
Chen, Qixin
;
Shao, Xintian
;
Ling, Peixue
;
Liu, Fei
;
Shao, Huarong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Xanthan gum
Low molecular weight
Oxidative stress
Chondrocytes
Apoptosis
Donepezil attenuates A beta-associated mitochondrial dysfunction and reduces mitochondrial A beta accumulation in vivo and in vitro
期刊论文
NEUROPHARMACOLOGY, 2015, 卷号: 95, 页码: 29-36
作者:
Ye, Chun Yan
;
Lei, Yun
;
Tang, Xi Can
;
Zhang, Hai Yan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Donepezil
Amyloid-beta
Oligomer
Mitochondrial dysfunction
ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 9, 页码: 1229-1236
作者:
Qi, Xin-ming
;
Miao, Ling-ling
;
Cai, Yan
;
Gong, Li-kun
;
Ren, Jin
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
tetrandrine
mitochondria
reactive oxygen species
cytochrome P450
rosgeneratedbycyp450especiallycyp2e1mediatemitochondrialdysfunctioninducedbytetrandrineinrathepatocytes
期刊论文
actapharmacologicasinica, 2013, 卷号: 34, 期号: 9, 页码: 1229
作者:
Qi Xinming
;
Miao Lingling
;
Cai Yan
;
Gong Likun
;
Ren Jin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
FATTY LIVER-DISEASE
KAPPA-B PATHWAY
OXIDATIVE STRESS
PERMEABILITY TRANSITION
CYTOCHROME-P450 2E1
INDUCED APOPTOSIS
CELL-DEATH
ER-STRESS
ACTIVATION
INJURY
tetrandrine
mitochondria
reactive oxygen species
cytochrome P450
Decreased Accumulation of Subcellular Amyloid-beta with Improved Mitochondrial Function Mediates the Neuroprotective Effect of Huperzine A
期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2012, 卷号: 31, 期号: 1, 页码: 131-142
作者:
Yang, Ling
;
Ye, Chun-yan
;
Huang, Xiao-tian
;
Tang, Xi-can
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Alzheimer's disease
amyloid-beta peptide
huperzine A
mitochondrial dysfunction
oligomer
High-Throughput Assay for Modulators of Mitochondrial Membrane Potential Identifies a Novel Compound With Beneficial Effects on db/db Mice
期刊论文
DIABETES, 2010, 卷号: 59, 期号: 1, 页码: 256-265
作者:
Qiu, Bei-Ying
;
Turner, Nigel
;
Li, Yuan-Yuan
;
Gu, Min
;
Huang, Meng-Wei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Huperzine A protects isolated rat brain mitochondria against beta-amyloid peptide
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2009, 卷号: 46, 期号: 11, 页码: 1454-1462
作者:
Gao, Xin
;
Zheng, Chun Yan
;
Yang, Ling
;
Tang, Xi Can
;
Zhang, Hai Yan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Huperzine A
beta-Amyloid peptide
Mitochondria
Oxidative phosphorylation
Free radicals
The relationship between diphenylamine structure and NSAIDs-induced hepatocytes injury
期刊论文
TOXICOLOGY LETTERS, 2009, 卷号: 186, 期号: 2, 页码: 111-114
作者:
Li, Yan
;
Qi, Xin-ming
;
Xue, Xiang
;
Wu, Xiong-fei
;
Wu, Yuan-feng
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Mitochondria
Liver injury
NSAIDs
Diphenylamine structure
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