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浏览/检索结果: 共7条，第1-7条 帮助 限定条件 发表日期：2021     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo 收藏  |  浏览/下载：42/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Enhanced activity and stability of Rhizomucor miehei lipase by mutating N-linked glycosylation site and its application in biodiesel production 期刊论文 FUEL, 2021, 卷号: 304, 页码: 11 作者:  Tian, Miao;  Fu, Junying;  Wang, Zhiyuan;  Miao, Changlin;  Lv, Pengmei 收藏  |  浏览/下载：61/0  |  提交时间：2021/10/27 Rhizomucor miehei lipase  N-linked glycosylation site  Thermostability  Methanol tolerance  Biodiesel   Glutamate Dehydrogenase Functions in Glutamic Acid Metabolism and Stress Resistance in Pyropia haitanensis 期刊论文 MOLECULES, 2021, 卷号: 26, 期号: 22, 页码: 16 作者:  Li, Shuang;  Shao, Zhanru;  Lu, Chang;  Yao, Jianting;  Zhou, Yongdong 收藏  |  浏览/下载：73/0  |  提交时间：2022/01/05 heterologous expression  protein purification  enzyme activity assay  site-directed mutagenesis  abiotic stresses   Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8 作者:  Wang, Xi;  Cheng, Xi;  Zhao, Lihua;  Wang, Yuzhe;  Ye, Chenyu 收藏  |  浏览/下载：25/0  |  提交时间：2021/11/04 parathyroid hormone receptor 2  cryo-electron microscopy  G protein-coupled receptor  ligand recognition  syndromic short stature   Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15 作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua 收藏  |  浏览/下载：35/0  |  提交时间：2021/11/04 Structural Determinants for Light-Dependent Membrane Binding of a Photoswitchable Polybasic Domain 期刊论文 ACS SYNTHETIC BIOLOGY, 2021, 卷号: 10 作者:  Li, Ling;  He, Lian;  Wu, Bo;  Yu, Chuandi;  Zhao, Hongxin 收藏  |  浏览/下载：53/0  |  提交时间：2021/04/26 polybasic domain  LOV2  optogenetics  NMR  PI(4,5)P-2  protein-lipid interaction   Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403 作者:  Li, Chunpu;  Hu, Sha-Sha;  Yang, Lisheng;  Wang, Min;  Long, Jian-Dong 收藏  |  浏览/下载：57/0  |  提交时间：2021/05/24 SIRT1  inhibitor  structure-activity relationship  interaction  deacetylase