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浏览/检索结果: 共67条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 23 作者:  Zou, Yi;  Hu, Yue;  Ge, Shushan;  Zheng, Yingbo;  Li, Yuezhen 收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01 IDO1  Heme  T cell  Cancer immunotherapy  Virtual screening  Drug design  Molecular dynamics simulation   A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文 CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+ 作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming 收藏  |  浏览/下载：77/0  |  提交时间：2020/07/01 Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease 期刊论文 PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14 作者:  Zhang, Yu;  Wu, Qimei;  Zhang, Lei;  Wang, Qing;  Yang, Zexian 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 Caffeic acid  A53T  Parkinson's disease  Autophagy  JNK   Targeting epigenetic machinery: Emerging novel allosteric inhibitors 期刊论文 PHARMACOLOGY & THERAPEUTICS, 2019, 卷号: 204, 页码: 24 作者:  Ye, Fei;  Huang, Jing;  Wang, Hongbo;  Luo, Cheng;  Zhao, Kehao 收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Epigenetics  PRC2  MLL complex  SWI/SNF  DNMT1  allosteric inhibitors   Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation 期刊论文 DIABETES, 2019, 卷号: 68, 期号: 12, 页码: 2197-2209 作者:  Jiang, Haowen;  Jin, Jia;  Duan, Yanan;  Xie, Zhifu;  Li, Yufeng 收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 LysargiNase and Chemical Derivatization Based Strategy for Facilitating In-Depth Profiling of C-Terminome 期刊论文 ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 22, 页码: 14522-14529 作者:  Hu, Hao;  Zhao, Wensi;  Zhu, Mengdi;  Zhao, Lei;  Zhai, Linhui 收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 21 作者:  Chen, Deheng;  Lu, Tian;  Yan, Ziqin;  Lu, Wenchao;  Lyu, Xilin 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 Bromodomain  BET protein  BD2  Selective  Crystal structure   Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 22, 页码: 6 作者:  Wang, Zhenkang;  Ma, Chunhua;  Wang, Yujie;  Xiao, Qiang;  Xu, Chenghui 收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01 Gentisides  Neurotrophic activity  Isosteric replacement  Conformational restriction  PC 12 cells   Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9983-9989 作者:  Zhou, Fang;  Ding, Kang;  Zhou, Yiqing;  Liu, Yang;  Liu, Xiaoyan 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 Genetically Encoded Residue-Selective Photo-Crosslinker to Capture Protein-Protein Interactions in Living Cells 期刊论文 CHEM, 2019, 卷号: 5, 期号: 11, 页码: 2955-2968 作者:  Hu, Wei;  Yuan, Yi;  Wang, Cai-Hu;  Tian, Hong-Tao;  Guo, An-Di 收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01