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科研机构
合肥物质科学研究院 [5]
内容类型
期刊论文 [5]
发表日期
2018 [5]
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发表日期:2018
专题:合肥物质科学研究院
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Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
作者:
Wang, Beilei
;
Wu, Jiaxin
;
Wu, Yun
;
Chen, Cheng
;
Zou, Fengming
收藏
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浏览/下载:65/0
  |  
提交时间:2019/12/25
CDK9
Kinase inhibitor
Structure-activity relationship
Leukemia
Exploratory clinical study of chidamide, an oral subtype-selective histone deacetylase inhibitor, in combination with exemestane in hormone receptor-positive advanced breast cancer
期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2018, 卷号: 30
-
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/10/26
PHASE-I
POSTMENOPAUSAL WOMEN
HDAC INHIBITOR
MULTICENTER
ENTINOSTAT
TAMOXIFEN
CS055/HBI-8000
RESISTANCE
LETROZOLE
TRIAL
Advanced breast cancer
hormone receptor-positive
chidamide
exemestane
Tumor suppressor miR-128-3p inhibits metastasis and epithelial-mesenchymal transition by targeting ZEB1 in esophageal squamous-cell cancer
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50
-
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  |  
浏览/下载:21/0
  |  
提交时间:2020/10/26
ACUTE LYMPHOBLASTIC-LEUKEMIA
GENOME-WIDE ASSOCIATION
EMT-ACTIVATOR ZEB1
CIRCULATING MICRORNAS
TRANSCRIPTION FACTORS
PROMOTES INVASION
MIRNA EXPRESSION
FEEDBACK LOOP
CARCINOMA
SURVIVAL
miR-128-3p
esophageal squamous-cell carcinoma
ZEB1
epithelial-mesenchymal transition
invasion and metastasis
Cohort Study on Prognosis of Patients with Metastatic Colorectal Cancer Treated with Integrated Chinese and Western Medicine
期刊论文
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2018, 卷号: 24
-
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  |  
浏览/下载:7/0
  |  
提交时间:2020/10/26
cohort study
metastatic colorectal cancer
integrative medicine
CCGD-ESCC: A Comprehensive Database for Genetic Variants Associated with Esophageal Squamous Cell Carcinoma in Chinese Population
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2018, 卷号: 16
-
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浏览/下载:8/0
  |  
提交时间:2020/10/26
GENOME-WIDE ASSOCIATION
SUSCEPTIBILITY LOCI
CANCER STATISTICS
LANDSCAPE
SURVIVAL
PLCE1
Esophageal cancer
Germline variants
Somatic mutations
Association database
Chinese population
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