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科研机构
上海药物研究所 [69]
内容类型
期刊论文 [69]
发表日期
2018 [69]
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浏览/检索结果:
共69条,第1-10条
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发表日期:2018
专题:上海药物研究所
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Direct Synthesis of 3-Acylindoles through Rhodium(III)-Catalyzed Annulation of N-Phenylamidines with alpha-Cl Ketones
期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 23, 页码: 7645-7649
作者:
Zhou, Jianhui
;
Li, Jian
;
Li, Yazhou
;
Wu, Chenglin
;
He, Guoxue
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/01/08
Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 48, 页码: 41118-41128
作者:
Chen, Wu
;
Yang, Wen
;
Chen, Pengyu
;
Huang, Yongzhuo
;
Li, Feng
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/01/08
disulfiram
copper diethyldithiocarbamate
drug resistance
prostate cancer
nanoparticle
drug delivery
paraptosis
Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery
期刊论文
SMALL, 2018, 卷号: 14, 期号: 47
作者:
Yin, Weimin
;
Yu, Xiaolu
;
Kang, Xuejia
;
Zhao, Yuge
;
Zhao, Pengfei
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
antiangiogenesis
EGFR(T790M) mutation
PD-L1 nanobody
simvastatin
tumor-associated macrophage
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands
期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Chen, Li-Li
;
Pan, You-Lu
;
Xie, Xiao-Yu
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/01/08
cannabinoids
CB1R
CB2R
heteroaryl pyrimidines
heteroaryl triazines
ligands
Development of high potent and selective Bcl-2 inhibitors bearing the structural elements of natural product artemisinin
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159, 页码: 149-165
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Huang, Wenjing
;
Luo, Jia
;
Li, Yang
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Apoptosis
Artemisinin
Bcl-2
Venetoclax
Selectivity
Immune modulation of a lipid-soluble extract of Pinellia pedatisecta Schott in the tumor microenvironment of an HPV+ tumor-burdened mouse model
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 225, 页码: 103-115
作者:
Huang, Haixia
;
Zhang, Mingxing
;
Yao, Sheng
;
Zhang, Meng
;
Peng, Jing
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2019/01/08
Pinellia pedatisecta extract (PE)
Cervical cancer
HPV+ tumor
TC-1 cell line
Helper T (Th) cellular immunity
Direct screening of malonylginsenosides from nine Ginseng extracts by an untargeted profiling strategy incorporating in-source collision-induced dissociation, mass tag, and neutral loss scan on a hybrid linear ion-trap/Orbitrap mass spectrometer coupled to ultra-high performance liquid chromatography
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1571, 页码: 213-222
作者:
Shi, Xiaojian
;
Yang, Wenzhi
;
Huang, Yong
;
Hou, Jinjun
;
Qiu, Shi
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
In-source collision-induced dissociation
Mass tag
Linear ion-trap/Orbitrap
Mass spectrometry
Panax
Malonylginsenoside
Untargeted profiling
Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 287, 页码: 12-23
作者:
Mo, Xiaopeng
;
Zheng, Zening
;
He, Yang
;
Zhone, Huihai
;
Kane, Xuejia
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
Lactoferrin nanoparticle
Reactive oxygen species
Tumor-associated macrophages
Brain-targeted delivery
Biomimetic delivery
Cell penetrating peptide
Fenretinide
Simvastatin
Rhodium(III)-Catalyzed C-H Activation of alpha-Iminonitriles or alpha-Imino Esters and Cyclization with Acrylates to 2H-Isoindoles
期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 19, 页码: 11736-11746
作者:
Li, Yazhou
;
Zhou, Jianhui
;
Fang, Feifei
;
Xu, Bin
;
Liu, Hong
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2019/01/08
A preclinical overview of metformin for the treatment of type 2 diabetes
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 106, 页码: 1227-1235
作者:
Zhou, Tingting
;
Xu, Xin
;
Du, Mengfan
;
Zhao, Tong
;
Wang, Jiaying
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/01/08
Gluconeogenesis
Insulin sensitivity
Mechanism
Metformin
Type 2 diabetes (T2D)
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