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Cu-Catalyzed [3+3] Annulation for the Synthesis of Pyrimidines via beta-C(sp(3))-H Functionalization of Saturated Ketones 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2016, 卷号: 81, 期号: 1-23, 页码: 11994-12000
作者:  Zhan, JL;  Wu, MW;  Chen, F;  Han, B
收藏  |  浏览/下载:3/0  |  提交时间:2017/05/08
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 17, 页码: 7856-7876
作者:  Golani, Lalit K.;  Wallace-Povirk, Adrianne;  Deis, Siobhan M.;  Wong, Jennifer;  Ke, Jiyuan
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08
Insights into mechanism of pyrido[2,3-d]pyrimidines as DYRK1A inhibitors based on molecular dynamic simulations 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2016, 卷号: 84, 期号: 8, 页码: 1108-1123
作者:  Li, JJ;  Tian, YL;  Zhai, HL;  Lv, M;  Zhang, XY
收藏  |  浏览/下载:3/0  |  提交时间:2017/01/12
Asymmetric Hydrogenation of Heteroarenes with Multiple Heteroatoms 期刊论文
SYNTHESIS-STUTTGART, 2016, 卷号: 48, 期号: 12, 页码: 1769-1781
作者:  Chen, Zhang-Pei;  Zhou, Yong-Gui
收藏  |  浏览/下载:16/0  |  提交时间:2019/06/20
The regulatory effect of cardamonin on TLR4/MyD88/NF-kappa B/iNOS pathway 期刊论文
Chinese Pharmacological Bulletin, 2016, 卷号: 32, 期号: 6
作者:  Deng Chao (1004596075@qq.com);  Ren Gai-yan;  Sun A-ning;  Luo Xiao-ping;  Wang Zheng-tao
收藏  |  浏览/下载:17/0  |  提交时间:2019/12/05
噻吩并嘧啶类表皮生长因子受体抑制剂的三维定量构效关系及分子对接研究 3D-QSAR and molecular docking studies on 6-alkenylamides substituted of 4-anilinothieno [2,3-d]pyrimidines as inhibitors of EGFR tyrosine kinase 期刊论文
2016, 卷号: 25, 页码: 1286-1292
作者:  王必武[1];  文晓荣[1];  舒茂[1];  胡勇[1];  林治华[1,2]
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/30
Structure-based discovery of novel 4,5,6-trisubstituted pyrimidines as potent covalent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13, 页码: 3052-3059
作者:  Zhang, Yihua;  Lai, Yisheng;  Zou, Yi;  Xiao, Jianhu;  Tu, Zhengchao
收藏  |  浏览/下载:13/0  |  提交时间:2018/12/13
Design, Synthesis, and Biological Evaluation of Substituted Pyrimidines as Potential Phosphatidylinositol 3-Kinase (PI3K) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 15, 页码: 7268-7274
作者:  Long, Zi-Jie;  Lai, Xiao-Ju;  Chen, Hui-Xuan;  Luo, Yu;  Weng, Jiang
收藏  |  浏览/下载:19/0  |  提交时间:2018/12/13
Structure-based discovery of novel 4,5,6-trisubstituted pyrimidines as potent covalent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13, 页码: 3052-3059
作者:  Luo, Minghao;  Lai, Yisheng;  Zhang, Yihua;  Ding, Ke;  Zou, Yi
收藏  |  浏览/下载:25/0  |  提交时间:2018/12/21
Structure-based discovery of novel 4,5,6-trisubstituted pyrimidines as potent covalent Bruton's tyrosine kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13, 页码: 3052-3059
作者:  Zou, Yi;  Xiao, Jianhu;  Tu, Zhengchao;  Yao, Kun;  Lai, Yisheng
收藏  |  浏览/下载:17/0  |  提交时间:2018/12/13


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