Osmotic Pressure and Its Biological Implications

doi:10.3390/ijms25063310

CORC > 力学研究所 > 中国科学院力学研究所 > 非线性力学国家重点实验室

	Osmotic Pressure and Its Biological Implications
	Zheng, Songjie 1,2; Li, Yan 2; Shao, Yingfeng 2; Li, Long 1,2; Song, Fan 1,2
刊名	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
	2024-03-01
卷号	25 期号:6 页码:18
关键词	osmotic pressure cell division cell differentiation lipid phase separation
ISSN号	1661-6596
DOI	10.3390/ijms25063310
通讯作者	Li, Long(lilong@lnm.imech.ac.cn) ; Song, Fan(songf@lnm.imech.ac.cn)
英文摘要	Gaining insight into osmotic pressure and its biological implications is pivotal for revealing mechanisms underlying numerous fundamental biological processes across scales and will contribute to the biomedical and pharmaceutical fields. This review aims to provide an overview of the current understanding, focusing on two central issues: (i) how to determine theoretically osmotic pressure and (ii) how osmotic pressure affects important biological activities. More specifically, we discuss the representative theoretical equations and models for different solutions, emphasizing their applicability and limitations, and summarize the effect of osmotic pressure on lipid phase separation, cell division, and differentiation, focusing on the mechanisms underlying the osmotic pressure dependence of these biological processes. We highlight that new theory of osmotic pressure applicable for all experimentally feasible temperatures and solute concentrations needs to be developed, and further studies regarding the role of osmotic pressure in other biological processes should also be carried out to improve our comprehensive and in-depth understanding. Moreover, we point out the importance and challenges of developing techniques for the in vivo measurement of osmotic pressure.
资助项目	National Natural Science Foundation of China
WOS关键词	FREE-SOLVENT MODEL ; RECEPTOR-LIGAND BINDING ; MECHANICAL-PROPERTIES ; LIPID RAFTS ; CELL-SHAPE ; BINARY ; VOLUME ; STRESS ; COEFFICIENTS ; MEMBRANES
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
WOS记录号	WOS:001192787100001
资助机构	National Natural Science Foundation of China
内容类型	期刊论文
源URL	[http://dspace.imech.ac.cn/handle/311007/94878]
专题	力学研究所_非线性力学国家重点实验室
通讯作者	Li, Long; Song, Fan
作者单位	1.Univ Chinese Acad Sci, Ctr Mat Sci & Optoelect Engn, Sch Engn Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Songjie,Li, Yan,Shao, Yingfeng,et al. Osmotic Pressure and Its Biological Implications[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2024,25(6):18.
APA	Zheng, Songjie,Li, Yan,Shao, Yingfeng,Li, Long,&Song, Fan.(2024).Osmotic Pressure and Its Biological Implications.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,25(6),18.
MLA	Zheng, Songjie,et al."Osmotic Pressure and Its Biological Implications".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 25.6(2024):18.