Fluorescent probes for biomolecule detection under environmental stress

doi:10.1016/j.jhazmat.2022.128527

	Fluorescent probes for biomolecule detection under environmental stress
	Han, Xiaoyue 1,2,5; Wang, Yue 1,5; Huang, Yan 4; Wang, Xiaoyan 4; Choo, Jaebum 3; Chen, Lingxin 1,4,6
刊名	JOURNAL OF HAZARDOUS MATERIALS
	2022-06-05
卷号	431 页码:40
关键词	Fluorescent probe Biomolecule Environmental stress Physiological pathological processes Chemical exposure
ISSN号	0304-3894
DOI	10.1016/j.jhazmat.2022.128527
通讯作者	Choo, Jaebum(jbchoo@cau.ac.kr) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要	The use of fluorescent probes in visible detection has been developed over the last several decades. Biomolecules are essential in the biological processes of organisms, and their distribution and concentration are largely influenced by environmental factors. Significant advances have occurred in the applications of fluorescent probes for the detection of the dynamic localization and quantity of biomolecules during various environmental stress-induced physiological and pathological processes. Herein, we summarize representative examples of small molecule-based fluorescent probes that provide bimolecular information when the organism is under environ -mental stress. The discussion includes strategies for the design of smart small-molecule fluorescent probes, in addition to their applications in biomolecule imaging under environmental stresses, such as hypoxia, ischemia-reperfusion, hyperthermia/hypothermia, organic/inorganic chemical exposure, oxidative/reductive stress, high glucose stimulation, and drug treatment-induced toxicity. We believe that comprehensive insight into the beneficial applications of fluorescent probes in biomolecule detection under environmental stress should enable the further development and effective application of fluorescent probes in the biochemical and biomedical fields.
WOS关键词	HIGHLY SELECTIVE DETECTION ; INDUCED LIVER-INJURY ; CYTOCHROME-P450 REDUCTASE DETECTION ; DRUG-INDUCED HEPATOTOXICITY ; ENDOGENOUS CARBON-MONOXIDE ; TURN-ON PROBE ; LIVING CELLS ; OXIDATIVE STRESS ; IN-VIVO ; ENDOPLASMIC-RETICULUM
WOS研究方向	Engineering ; Environmental Sciences & Ecology
语种	英语
WOS记录号	WOS:000765062500002
资助机构	National Natural Science Foundation of China, China ; Science and Technology Innovation Development Plan of Yantai of China, China ; National Research Foundation of Korea, Korea ; Taishan Scholar Project Special Funding, China
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/34796]
专题	中国科学院烟台海岸带研究所
通讯作者	Choo, Jaebum; Chen, Lingxin
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Univ Oxford, Present Ludwig Inst Canc Res, Nuffield Dept Clin Med, Oxford, England 3.Chung Ang Univ, Dept Chem, Seoul 06974, South Korea 4.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Han, Xiaoyue,Wang, Yue,Huang, Yan,et al. Fluorescent probes for biomolecule detection under environmental stress[J]. JOURNAL OF HAZARDOUS MATERIALS,2022,431:40.
APA	Han, Xiaoyue,Wang, Yue,Huang, Yan,Wang, Xiaoyan,Choo, Jaebum,&Chen, Lingxin.(2022).Fluorescent probes for biomolecule detection under environmental stress.JOURNAL OF HAZARDOUS MATERIALS,431,40.
MLA	Han, Xiaoyue,et al."Fluorescent probes for biomolecule detection under environmental stress".JOURNAL OF HAZARDOUS MATERIALS 431(2022):40.