Genomics of post-bottleneck recovery in the northern elephant seal

doi:10.1038/s41559-024-02337-4

CORC > 深海科学与工程研究所 > 中国科学院深海科学与工程研究所 > 深海科学研究部 > 深海生物学研究室 > 海洋哺乳动物与海洋生物声学研究组

	Genomics of post-bottleneck recovery in the northern elephant seal
	Hoelzel, A. Rus 8; Gkafas, Georgios A.7; Kang, Hui 5,6; Sarigol, Fatih 8; Le Boeuf, Burney 4; Costa, Daniel P.4; Beltran, Roxanne S.4; Reiter, Joanne 4; Robinson, Patrick W.4; McInerney, Nancy 3
刊名	NATURE ECOLOGY & EVOLUTION
	2024-02-21
页码	22
ISSN号	2397-334X
DOI	10.1038/s41559-024-02337-4
英文摘要	Populations and species are threatened by human pressure, but their fate is variable. Some depleted populations, such as that of the northern elephant seal (Mirounga angustirostris), recover rapidly even when the surviving population was small. The northern elephant seal was hunted extensively and taken by collectors between the early 1800s and 1892, suffering an extreme population bottleneck as a consequence. Recovery was rapid and now there are over 200,000 individuals. We sequenced 260 modern and 8 historical northern elephant seal nuclear genomes to assess the impact of the population bottleneck on individual northern elephant seals and to better understand their recovery. Here we show that inbreeding, an increase in the frequency of alleles compromised by lost function, and allele frequency distortion, reduced the fitness of breeding males and females, as well as the performance of adult females on foraging migrations. We provide a detailed investigation of the impact of a severe bottleneck on fitness at the genomic level and report on the role of specific gene systems. Genome analysis of modern and historical elephant seals reveals impacts of a severe bottleneck on the genomes and fitness of individual seals, and the implications for recovery.
资助项目	National Natural Science Foundation of China[N00014-18-1-2822] ; National Natural Science Foundation of China[N000014-13-1-0134] ; One Belt and One Road Science and Technology Cooperation Special Program of the International Partnership Program of the Chinese Academy of Sciences[RC20-2-1284] ; Specially-Appointed Professor Program of Jiangsu Province ; National Science Foundation ; National Geographic Society ; Office of Naval Research ; Strategic Environmental Research Development Program ; Gordon and Betty Moore Foundation ; David and Lucile Packard Foundation ; Alfred P Sloan Foundation ; Animal Telemetry Network ; [42225604] ; [41422604] ; [183446KYSB20200016]
WOS关键词	GENETIC-VARIATION ; READ ALIGNMENT ; POPULATION ; ASSOCIATION ; HISTORY ; FRAMEWORK ; INFERENCE ; IMPACT
WOS研究方向	Environmental Sciences & Ecology ; Evolutionary Biology
语种	英语
出版者	NATURE PORTFOLIO
WOS记录号	WOS:001173658000001
资助机构	National Natural Science Foundation of China ; One Belt and One Road Science and Technology Cooperation Special Program of the International Partnership Program of the Chinese Academy of Sciences ; Specially-Appointed Professor Program of Jiangsu Province ; National Science Foundation ; National Geographic Society ; Office of Naval Research ; Strategic Environmental Research Development Program ; Gordon and Betty Moore Foundation ; David and Lucile Packard Foundation ; Alfred P Sloan Foundation ; Animal Telemetry Network
内容类型	期刊论文
源URL	[http://ir.idsse.ac.cn/handle/183446/10913]
专题	深海科学研究部_深海生物学研究室_海洋哺乳动物与海洋生物声学研究组
通讯作者	Hoelzel, A. Rus; Sun, Shuai; Fan, Guangyi; Li, Songhai
作者单位	1.BGI Res, Qingdao, Peoples R China 2.Nanjing Normal Univ, Coll Life Sci, Integrat Biol Lab, Nanjing, Peoples R China 3.Smithsonian Inst, Natl Zoo & Conservat Biol Inst, Ctr Conservat Genom, Washington, DC USA 4.Univ Calif Santa Cruz, Ecol & Evolutionary Biol, Santa Cruz, CA USA 5.Inst Hydrobiol, Chinese Acad Sci, Innovat Res Ctr Aquat Mammals, Wuhan, Peoples R China 6.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Marine Mammal & Marine Bioacoust Lab, Sanya, Peoples R China 7.Univ Thessaly, Dept Ichthyol & Aquat Environm, Volos, Greece 8.Univ Durham, Biosci, Durham, England
推荐引用方式 GB/T 7714	Hoelzel, A. Rus,Gkafas, Georgios A.,Kang, Hui,et al. Genomics of post-bottleneck recovery in the northern elephant seal[J]. NATURE ECOLOGY & EVOLUTION,2024:22.
APA	Hoelzel, A. Rus.,Gkafas, Georgios A..,Kang, Hui.,Sarigol, Fatih.,Le Boeuf, Burney.,...&Li, Songhai.(2024).Genomics of post-bottleneck recovery in the northern elephant seal.NATURE ECOLOGY & EVOLUTION,22.
MLA	Hoelzel, A. Rus,et al."Genomics of post-bottleneck recovery in the northern elephant seal".NATURE ECOLOGY & EVOLUTION (2024):22.