Unveiling ochratoxin a controlling and biodetoxification molecular mechanisms: Opportunities to secure foodstuffs from OTA contamination

doi:10.1016/j.fct.2022.113437

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	Unveiling ochratoxin a controlling and biodetoxification molecular mechanisms: Opportunities to secure foodstuffs from OTA contamination
	Yang, Qiya ; Dhanasekaran, Solairaj ; Ngea, Guillaume Legrand Ngolong 3; Tian, Shiping 1; Li, Boqiang 1; Zhang, Hongyin
刊名	FOOD AND CHEMICAL TOXICOLOGY
	2022
卷号	169
ISSN号	0278-6915
DOI	10.1016/j.fct.2022.113437
文献子类	Review
英文摘要	Anarchic growth of ochratoxin A (OTA) producing fungi during crop production, prolonged storage, and processing results in OTA contamination in foodstuffs. OTA in food exacerbates the risk of health and economic problems for consumers and farmers worldwide. Although the toxic effects of OTA on human health have not been well established, comprehensive preventive and remedial measures will be essential to eliminate OTA from foodstuffs. Strict regulations, controlling OTA at pre-or post-harvest stage, and decontamination of OTA have been adopted to prevent human and animal OTA exposure. Biological control of OTA and bio-decontamination are the most promising strategies due to their safety, specificity and nutritional value. This review addresses the current understanding of OTA biodegradation mechanisms and recent developments in OTA control and bio-decontamination strategies. Additionally, this review analyses the strength and weaknesses of different OTA control methods and the contemporary approaches to enhance the efficiency of biocontrol agents. Overall, this review will support the implementation of new strategies to effectively control OTA in food sectors. Further studies on efficacy-related issues, production issues and cost-effectiveness of OTA biocontrol are to be carried out to improve the knowledge, develop improved delivery technologies and safeguard the durability of OTA biocontrol approaches.
学科主题	Food Science & Technology ; Toxicology
电子版国际标准刊号	1873-6351
出版地	OXFORD
WOS关键词	BACILLUS-SUBTILIS ; SACCHAROMYCES-CEREVISIAE ; FUNCTIONAL-CHARACTERIZATION ; ASPERGILLUS-CARBONARIUS ; YARROWIA-LIPOLYTICA ; REMOVE OCHRATOXIN ; YEAST-CELLS ; DEGRADATION ; BIODEGRADATION ; ADSORPTION
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000876186700003
资助机构	National Natural Science Foundation of China ; [32150410368] ; [32172641] ; [32072276]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/29012]
专题	中科院北方资源植物重点实验室
作者单位	1.Univ Douala Yabassi, Inst Sci Halieut, Dept Transformat & Controle Qualitedes Prod Halie, POB 7236, Douala Bassa, Cameroon 2.Chinese Acad Sci, Inst Bot, Xiangshan Nanxincun 20, Beijing 100093, Peoples R China 3.Jiangsu Univ, Sch Food & Biol Engn, 301 Xue Fu Rd, Zhenjiang 212013, Peoples R China
推荐引用方式 GB/T 7714	Yang, Qiya,Dhanasekaran, Solairaj,Ngea, Guillaume Legrand Ngolong,et al. Unveiling ochratoxin a controlling and biodetoxification molecular mechanisms: Opportunities to secure foodstuffs from OTA contamination[J]. FOOD AND CHEMICAL TOXICOLOGY,2022,169.
APA	Yang, Qiya,Dhanasekaran, Solairaj,Ngea, Guillaume Legrand Ngolong,Tian, Shiping,Li, Boqiang,&Zhang, Hongyin.(2022).Unveiling ochratoxin a controlling and biodetoxification molecular mechanisms: Opportunities to secure foodstuffs from OTA contamination.FOOD AND CHEMICAL TOXICOLOGY,169.
MLA	Yang, Qiya,et al."Unveiling ochratoxin a controlling and biodetoxification molecular mechanisms: Opportunities to secure foodstuffs from OTA contamination".FOOD AND CHEMICAL TOXICOLOGY 169(2022).