m6A-mediated regulation of crop development and stress responses

doi:10.1111/pbi.13792

CORC > 植物研究所 > 中国科学院植物研究所 > 中科院北方资源植物重点实验室

	m6A-mediated regulation of crop development and stress responses
	Zhou, Leilei 2; Gao, Guangtong 2; Tang, Renkun 2; Wang, Weihao 2; Wang, Yuying 2; Tian, Shiping 2; Qin, Guozheng 2
刊名	PLANT BIOTECHNOLOGY JOURNAL
	2022
卷号	20 期号:8 页码:1447-1455
关键词	N-6-methyladenosine m(6)A machineries crop development stress responses crop improvement
ISSN号	1467-7644
DOI	10.1111/pbi.13792
文献子类	Review
英文摘要	Dynamic chemical modifications in eukaryotic messenger RNAs (mRNAs) constitute an essential layer of gene regulation, among which N-6-methyladenosine (m(6)A) was unveiled to be the most abundant. m(6)A functionally modulates important biological processes in various mammals and plants through the regulation of mRNA metabolism, mainly mRNA degradation and translation efficiency. Physiological functions of m(6)A methylation are diversified and affected by intricate sequence contexts and m(6)A machineries. A number of studies have dissected the functional roles and the underlying mechanisms of m(6)A modifications in regulating plant development and stress responses. Recently, it was demonstrated that the human FTO-mediated plant m(6)A removal caused dramatic yield increases in rice and potato, indicating that modulation of m(6)A methylation could be an efficient strategy for crop improvement. In this review, we summarize the current progress concerning the m(6)A-mediated regulation of crop development and stress responses, and provide an outlook on the potential application of m(6)A epitranscriptome in the future improvement of crops.
学科主题	Biotechnology & Applied Microbiology ; Plant Sciences
电子版国际标准刊号	1467-7652
出版地	HOBOKEN
WOS关键词	MESSENGER-RNA METHYLATION ; NUCLEAR-RNA ; M(6)A METHYLATION ; CELL FATE ; N6-METHYLADENOSINE ; DEMETHYLASE ; POLYADENYLATION ; TRANSCRIPTOME ; RECOGNITION ; TRANSLATION
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
语种	英语
出版者	WILEY
WOS记录号	WOS:000761951700001
资助机构	National Natural Science Foundation of China [31925035, 31871855] ; National Key Research and Development Program [2018YFD1000200]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/28503]
专题	中科院北方资源植物重点实验室
作者单位	1.Univ Chinese Acad Sci, Beijing, Peoples R China 2.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Leilei,Gao, Guangtong,Tang, Renkun,et al. m6A-mediated regulation of crop development and stress responses[J]. PLANT BIOTECHNOLOGY JOURNAL,2022,20(8):1447-1455.
APA	Zhou, Leilei.,Gao, Guangtong.,Tang, Renkun.,Wang, Weihao.,Wang, Yuying.,...&Qin, Guozheng.(2022).m6A-mediated regulation of crop development and stress responses.PLANT BIOTECHNOLOGY JOURNAL,20(8),1447-1455.
MLA	Zhou, Leilei,et al."m6A-mediated regulation of crop development and stress responses".PLANT BIOTECHNOLOGY JOURNAL 20.8(2022):1447-1455.