Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering

doi:10.1016/j.molp.2022.05.006

CORC > 植物研究所 > 中国科学院植物研究所 > 中科院光生物学重点实验室

	Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering
	Hu, Zhi 2; Yang, Zhipan ; Zhang, Yi 3; Zhang, Aihong 3; Lu, Qingtao ; Fang, Ying 3; Lu, Congming 3
刊名	MOLECULAR PLANT
	2022
卷号	15 期号:7 页码:1137-1156
关键词	autophagy heading date rice Hd1 homeostasis
ISSN号	1674-2052
DOI	10.1016/j.molp.2022.05.006
文献子类	Article
英文摘要	Flowering time (heading date) is a critical agronomic trait that determines the yield and regional adaptability of crops. Heading date 1 (Hd1) is a central regulator of photoperiodic flowering in rice (Oryza sativa). Howev-er, how the homeostasis of Hd1 protein is achieved is poorly understood. Here, we report that the nuclear autophagy pathway mediates Hd1 degradation in the dark to regulate flowering. Loss of autophagy function results in an accumulation of Hd1 and delays flowering under both short-day and long-day conditions. In the dark, nucleus-localized Hd1 is recognized as a substrate for autophagy and is subjected to vacuolar degra-dation via the autophagy protein OsATG8. The Hd1-OsATG8 interaction is required for autophagic degrada-tion of Hd1 in the dark. Our study reveals a new mechanism by which Hd1 protein homeostasis is regulated by autophagy to control rice flowering. Our study also indicates that the regulation of flowering by autophagic degradation of Hd1 orthologs may have arisen over the course of mesangiosperm evolution, which would have increased their flexibility and adaptability to the environment by modulating flowering time.
学科主题	Biochemistry & Molecular Biology ; Plant Sciences
电子版国际标准刊号	1752-9867
出版地	CAMBRIDGE
WOS关键词	SELECTIVE AUTOPHAGY ; PLANT-GROWTH ; LIR MOTIF ; CONSTANS ; TIME ; PROTEINS ; HD3A ; DEGRADES ; SYSTEM ; COP1
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
语种	英语
出版者	CELL PRESS
WOS记录号	WOS:000824510600010
资助机构	National Key Research and Development Program of China [2020YFA0907602] ; National Natural Science Foundation of China [31730102]
内容类型	期刊论文
源URL	[http://ir.ibcas.ac.cn/handle/2S10CLM1/28478]
专题	中科院光生物学重点实验室
作者单位	1.Shandong Agr Univ, Coll Life Sci, State Key Lab Crop Biol, Tai An 271018, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Beijing 100093, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Hu, Zhi,Yang, Zhipan,Zhang, Yi,et al. Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering[J]. MOLECULAR PLANT,2022,15(7):1137-1156.
APA	Hu, Zhi.,Yang, Zhipan.,Zhang, Yi.,Zhang, Aihong.,Lu, Qingtao.,...&Lu, Congming.(2022).Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering.MOLECULAR PLANT,15(7),1137-1156.
MLA	Hu, Zhi,et al."Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering".MOLECULAR PLANT 15.7(2022):1137-1156.