Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing

	Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing
	Xie, Xianghong; Lei, Yulu; Li, Ying; Zhang, Mingyu; Sun, Jing; Zhu, Ming-Qiang; Wang, Jianlong
刊名	JOURNAL OF COLLOID AND INTERFACE SCIENCE
	2023
卷号	637 页码:20
英文摘要	Adhesive hydrogels have emerged as promising candidates to solve life-threatening infectious skin inju-ries. However, the inadequate mechanical characteristics and biological adherence limit the traditional wound dressing unable to adapt to high-frequency movement and real-time monitoring of wound heal-ing, calling for the development of bioadhesive materials guided wound healing. In this work, a multi-functional bioadhesive hydrogel with double colorimetric-integrated of polyethylene glycol (PVA)-dextran (Dex)-borax-bromothymol blue (BTB)-fluorescein thiocyanate (FITC) and functionalization by tungsten disulfide-catechol nanozyme (CL/WS2) was created. Hydrogel is a perfect biological adhesive, which can achieve repeatable and strong tissue adhesion strength (8.3 +/- 0.6 kPa), which is 1.66 times that of commercial dressings. Based on the strong biological adhesion of the hydrogel, a sensor is integrated into the hydrogel to collect visual image of bacterial infection from a smartphone and transform it into an on-site pH signal for remote evaluation of the wound's dynamic status in real time. Ultimately, the adhe-siveness hydrogel has high worth in managing the burden related to wound healing and paving the way for intelligent wound management in the future.(c) 2023 Published by Elsevier Inc.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/61709]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Xie, Xianghong,Lei, Yulu,Li, Ying,et al. Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2023,637:20.
APA	Xie, Xianghong.,Lei, Yulu.,Li, Ying.,Zhang, Mingyu.,Sun, Jing.,...&Wang, Jianlong.(2023).Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing.JOURNAL OF COLLOID AND INTERFACE SCIENCE,637,20.
MLA	Xie, Xianghong,et al."Dual-crosslinked bioadhesive hydrogel as NIR/pH stimulus- responsiveness platform for effectively accelerating wound healing".JOURNAL OF COLLOID AND INTERFACE SCIENCE 637(2023):20.