The application of chair homogeneity index: The advantages of DMLC over VMAT in the radiotherapy for esophageal cancer

doi:10.1016/j.jrras.2021.11.004

	The application of chair homogeneity index: The advantages of DMLC over VMAT in the radiotherapy for esophageal cancer
	Xi, Dan 2; Jiao, Tongli 4; Mu, Jinming 2; Chen, Yuan 2; Gu, Wendong 2; Li, Qilin 1,2,3
刊名	JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES
	2022-03-01
卷号	15
关键词	Esophageal cancer Dynamic multileaf-collimator Volumetric modulation arc therapy Chair homogeneity index
ISSN号	1687-8507
DOI	10.1016/j.jrras.2021.11.004
通讯作者	Gu, Wendong(hony0428@126.com) ; Li, Qilin(Leo3602@126.com)
英文摘要	Dynamic multileaf-collimator (DMLC) and volumetric modulation arc therapy (VMAT) were compared carefully in radiotherapy for esophagus cancer (EC) with the help of a new plan quality index: chair homogeneity index (CHI). Thirty-five patients with EC who underwent RT were enrolled. The prescription for the planning tumor volume (PTV) was 54Gy/25f and for the boost volume was 60Gy/25f. Two plans were designed for each patient: DMLC and VMAT. The dose-volume constraints were the same for two kinds of plans of each patient. CHI was an index developed by us and described the dose heterogeneity in the PTV but excluding the Boost (P-B). Heterogeneity index (HI), conformity index (CI) and other plan qualities indexes were also collected. The mean CHIs of PTV and P-B were 1.70 and 1.79 in DMLC, significantly higher than 0.82 and 0.86 in VMAT, respectively. The mean HIs of PTV and PTV-Boost were 17.79% and 15.55% in DMLC, slightly higher than 19.33% and 16.83% in VMAT, respectively. From the data aforementioned, DMLC is superior to VMAT in the treatment for EC. The high values of CHI in plans with DMLC proposed that DMLC achieve a more ideal dose distribution inside a compound target than VMAT.
资助项目	Science and Technology Bureau foundation application project of Changzhou[CJ20179047] ; CSCO-Hengrui Cancer Research Fund[Y-HR2018-063] ; Jiangsu Commission of Health Support Projects[H2019104]
WOS关键词	MODULATED ARC THERAPY ; SIMULTANEOUS INTEGRATED BOOST ; NECK-CANCER ; IMRT ; MODEL ; HEAD
WOS研究方向	Science & Technology - Other Topics ; Radiology, Nuclear Medicine & Medical Imaging
语种	英语
出版者	ELSEVIER
WOS记录号	WOS:000792423900006
资助机构	Science and Technology Bureau foundation application project of Changzhou ; CSCO-Hengrui Cancer Research Fund ; Jiangsu Commission of Health Support Projects
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/130853]
专题	中国科学院合肥物质科学研究院
通讯作者	Gu, Wendong; Li, Qilin
作者单位	1.Univ Sci & Technol China, Hefei 230026, Peoples R China 2.Soochow Univ, Affiliated Hosp 3, Peoples Hosp Changzhou 1, Dept Radiat Oncol, 185 Ju Qian Jie, Changzhou 213003, Jiangsu, Peoples R China 3.Chinese Acad Sci, Hefei Inst Phys Sci, Hefei 230031, Peoples R China 4.Second Peoples Hosp Jiaozuo, Dept Cardiothorac Surg 2, 17 Minzhu South Rd, Jiaozuo 454001, Henan, Peoples R China
推荐引用方式 GB/T 7714	Xi, Dan,Jiao, Tongli,Mu, Jinming,et al. The application of chair homogeneity index: The advantages of DMLC over VMAT in the radiotherapy for esophageal cancer[J]. JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES,2022,15.
APA	Xi, Dan,Jiao, Tongli,Mu, Jinming,Chen, Yuan,Gu, Wendong,&Li, Qilin.(2022).The application of chair homogeneity index: The advantages of DMLC over VMAT in the radiotherapy for esophageal cancer.JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES,15.
MLA	Xi, Dan,et al."The application of chair homogeneity index: The advantages of DMLC over VMAT in the radiotherapy for esophageal cancer".JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES 15(2022).