Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives

doi:10.1016/j.trac.2021.116371

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives
	Qin, Xiaoxiao 4; Liu, Jiajing 4; Zhang, Zhong 3,4; Li, Jinhua 3; Yuan, Li 4; Zhang, Zhiyang 3; Chen, Lingxin 1,2,3
刊名	TRAC-TRENDS IN ANALYTICAL CHEMISTRY
	2021-10-01
卷号	143 页码:15
关键词	Microfluidic paper-based chips Rapid detection Food safety Portable device Pathogen
ISSN号	0165-9936
DOI	10.1016/j.trac.2021.116371
通讯作者	Zhang, Zhong() ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要	Microfluidic paper-based chips (mu PCs) are micro-laboratory analysis systems that use paper instead of traditional microfluidic substrate materials and miniaturize biochemical reactions. Based on traditional 2D mu PCs, the novel mu PCs are innovative 3D structure chips that are realized by fluid channel construction, channel microvalve, folding and other fluid control methods. In recent years, mu PCs have developed rapidly in terms of design and integration and have been widely used in food safety, environmental residue pollution, pathogen detection and other applications. Due to their advantages of low cost, portability and satisfactory thermal stability, they have unique potential in the field of rapid detection. Herein, based on the detailed preparation, we focus on the selection of the paper substrate, microfluidic chip hydrophilic/hydrophobic processing and substrate modification. We highlight the latest research progress of mu PCs in rapid detection from 2014 to 2021, and discuss the remaining challenges and future perspectives for further development. (C) 2021 Elsevier B.V. All rights reserved.
WOS关键词	LOW-COST ; FLUORESCENCE DETECTION ; MULTIPLEXED DETECTION ; SENSITIVE DETECTION ; BETA-AGONISTS ; DEVICES ; PLATFORM ; SENSOR ; FABRICATION ; ASSAY
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000729685900011
资助机构	National Natural Science Foundation of China ; Shaanxi Province Key Research and Development Project ; Postdoctoral Program of Shaanxi Province ; Fundamental Research Fund of the Central University ; Taishan Scholar Project Special Funding
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/31300]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
通讯作者	Zhang, Zhong; Chen, Lingxin
作者单位	1.Qingdao Univ Technol, Sch Environm & Municipal Engn, Qingdao 266033, Peoples R China 2.Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Key Lab Coastal Environm Proc, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China 4.Shaanxi Normal Univ, Engn Res Ctr High Value Utilizat Western Fruit Re, Shaanxi Engn Lab Food Green Proc & Safety Control, Coll Food Engn & Nutr Sci,Minist Educ, Xian 710062, Shaanxi, Peoples R China
推荐引用方式 GB/T 7714	Qin, Xiaoxiao,Liu, Jiajing,Zhang, Zhong,et al. Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2021,143:15.
APA	Qin, Xiaoxiao.,Liu, Jiajing.,Zhang, Zhong.,Li, Jinhua.,Yuan, Li.,...&Chen, Lingxin.(2021).Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,143,15.
MLA	Qin, Xiaoxiao,et al."Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 143(2021):15.