Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing

	Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing
	Li, Lei-Lei; Ma, Shi-Ke; Peng, Wei; Fang, You-Gui; Duo, Hai-Rui; Fu, Hong-Yun; Jia, Gong-Xue
刊名	TROPICAL ANIMAL HEALTH AND PRODUCTION
	2021
卷号	53 期号:1
关键词	Tibetan sheep SNP Adaptability Candidate genes
英文摘要	Tibetan sheep is one of primitive Chinese sheep breeds, which achieved the divergence about 2500 years ago in Qinghai plateau region. According to different geographic conditions, especially altitudes, Tibetan sheep evolved into different breeds. In this study, we performed whole genome resequencing of 5 representative Tibetan sheep breeds. Comparative genomic analysis showed that they can be divided into different clades with a close genetic relationship. However, some genes with common selective regions were enriched for hypoxic adaptability in different breeds living at higher altitude, including GHR, BMP15, and CPLANE1. Furthermore, breed-specific selective regions about physical characteristics, especially wool growth, were found in genes such as BSND, USP24, NCAPG, and LCORL. This study could contribute to our understanding about trait formation and offer a reference for breeding of Tibetan sheep.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/60850]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Li, Lei-Lei,Ma, Shi-Ke,Peng, Wei,et al. Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing[J]. TROPICAL ANIMAL HEALTH AND PRODUCTION,2021,53(1).
APA	Li, Lei-Lei.,Ma, Shi-Ke.,Peng, Wei.,Fang, You-Gui.,Duo, Hai-Rui.,...&Jia, Gong-Xue.(2021).Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing.TROPICAL ANIMAL HEALTH AND PRODUCTION,53(1).
MLA	Li, Lei-Lei,et al."Genetic diversity and population structure of Tibetan sheep breeds determined by whole genome resequencing".TROPICAL ANIMAL HEALTH AND PRODUCTION 53.1(2021).