Cellular Uptake of Few-Layered Black Phosphorus and the Toxicity to an Aquatic Unicellular Organism

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Cellular Uptake of Few-Layered Black Phosphorus and the Toxicity to an Aquatic Unicellular Organism
	Wu, Qi; Yao, Linlin; Zhao, Xingchen; Zeng, Li; Li, Ping; Yang, Xiaoxi; Zhang, Liu; Cai, Zongwei; Shi, Jianbo; Qu, Guangbo
刊名	ENVIRONMENTAL SCIENCE & TECHNOLOGY
	2020-02-04
卷号	54 期号:3 页码:1583-1592
ISSN号	0013-936X
英文摘要	With the potential continuous application of mono- or few-layered black phosphorus (BP) in electronic, photonic, therapeutic, and environmental fields, the possible side effects of BP on aquatic organisms after release into natural water are of great concern. We investigated the potential toxicity of BP on the unicellular organism, Tetrahymena thermophila. After the exposure for 8 h at 10 mu g/mL, the reproduction of T. thermophila significantly decreased by 46.3%. Severe cell membrane and cilium damage were observed by scanning electron microscopy (SEM) upon treatment with BP. Based on bright-field microscopy and three-dimensional Raman imaging, we investigated the cellular uptake and translocation of BP within T. thermophila. It was observed that the engulfment of BP by T. thermophila was oral apparatus dependent, through which intracellular BP was then transported to the posterior end of T. thermophila by food vacuole packaging. Our study also revealed that BP induced the increase of intracellular reactive oxidant species and formed oxidative stress-dependent toxicity to T. thermophila. Our findings paved a way for better understanding the BP toxicityon aquatic organisms and its potential ecological risks.
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/44628]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Wu, Qi,Yao, Linlin,Zhao, Xingchen,et al. Cellular Uptake of Few-Layered Black Phosphorus and the Toxicity to an Aquatic Unicellular Organism[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2020,54(3):1583-1592.
APA	Wu, Qi.,Yao, Linlin.,Zhao, Xingchen.,Zeng, Li.,Li, Ping.,...&Jiang, Guibin.(2020).Cellular Uptake of Few-Layered Black Phosphorus and the Toxicity to an Aquatic Unicellular Organism.ENVIRONMENTAL SCIENCE & TECHNOLOGY,54(3),1583-1592.
MLA	Wu, Qi,et al."Cellular Uptake of Few-Layered Black Phosphorus and the Toxicity to an Aquatic Unicellular Organism".ENVIRONMENTAL SCIENCE & TECHNOLOGY 54.3(2020):1583-1592.