Hybrid monolithic columns coated with cellulose tris(3,5-dimethylphenyl-carbamate) for enantioseparations in capillary electrochromatography and capillary liquid chromatography

	Hybrid monolithic columns coated with cellulose tris(3,5-dimethylphenyl-carbamate) for enantioseparations in capillary electrochromatography and capillary liquid chromatography
	Ou, Junjie 1; Lin, Hui 1,2; Tang, Shouwan 3; Zhang, Zhenbin 1,2; Dong, Jing 1; Zou, Hanfa 1
刊名	journal of chromatography a
	2012-12-21
卷号	1269 页码:372-378
关键词	Hybrid monolithic column Chiral stationary phase Capillary electrochromatography Capillary liquid chromatography Substituted cellulose derivatives Enantioseparation
ISSN号	0021-9673
通讯作者	欧俊杰 ; 邹汉法
产权排序	1,1
英文摘要	a hybrid monolithic capillary column synthesized with (3-chloropropyl)-trimethoxysilane (cptms) and tetramethoxysilane (tmos) via sol-gel chemistry was in situ coated with cellulose tris(3,5-dimethylphenyl-carbamate) (cdmpc) for enantioseparations in capillary electrochromatography (cec) and capillary liquid chromatography (clc). prior to coating, the prepared cp-silica hybrid monolith was straightforwardly modified with diethylenetriamine (deta) to introduce -nh2 functionalities via the nucleophilic substitution reaction, which generate the stronger eof for cec. the coating condition was optimized to obtain a stable and reproducible chiral stationary phase for enantioseparation. the results indicated that racemic benzoin was baseline separated on the resulting hybrid monolith coated with 30 mg/ml cdmpc in cec, while several racemates were successfully enantioseparated on the resulting cp-silica hybrid monolithic column coated with 60 mg/ml cdmpc in clc with rp and np modes. (c) 2012 elsevier b.v. all rights reserved.
学科主题	物理化学
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	chiral stationary phases ; electromigration techniques ; polysaccharide derivatives ; enantiomer separation ; silica ; cec ; polymer ; fabrication ; trends ; hplc
收录类别	SCI
语种	英语
WOS记录号	WOS:000312475300034
公开日期	2013-10-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/118329]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Taizhou Coll, Linhai 317000, Peoples R China
推荐引用方式 GB/T 7714	Ou, Junjie,Lin, Hui,Tang, Shouwan,et al. Hybrid monolithic columns coated with cellulose tris(3,5-dimethylphenyl-carbamate) for enantioseparations in capillary electrochromatography and capillary liquid chromatography[J]. journal of chromatography a,2012,1269:372-378.
APA	Ou, Junjie,Lin, Hui,Tang, Shouwan,Zhang, Zhenbin,Dong, Jing,&Zou, Hanfa.(2012).Hybrid monolithic columns coated with cellulose tris(3,5-dimethylphenyl-carbamate) for enantioseparations in capillary electrochromatography and capillary liquid chromatography.journal of chromatography a,1269,372-378.
MLA	Ou, Junjie,et al."Hybrid monolithic columns coated with cellulose tris(3,5-dimethylphenyl-carbamate) for enantioseparations in capillary electrochromatography and capillary liquid chromatography".journal of chromatography a 1269(2012):372-378.