The gut microbiota and its products: Establishing causal relationships with obesity related outcomes

doi:10.1111/obr.13341

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物学与生物资源利用所重点实验室

	The gut microbiota and its products: Establishing causal relationships with obesity related outcomes
	Li, Lili 1,2; Zhang, Yubing 1,3; Speakman, John Roger 4; Hu, Shanliang 5; Song, Yipeng 5; Qin, Song 1,2
刊名	OBESITY REVIEWS
	2021-09-06
页码	14
关键词	causality gut microbiota metabolites obesity
ISSN号	1467-7881
DOI	10.1111/obr.13341
通讯作者	Song, Yipeng(syp1972@sina.com) ; Qin, Song(sqin@yic.ac.cn)
英文摘要	Gut microorganisms not only participate in the metabolism of carbohydrate, lipids, protein, and polypeptides in the intestine but also directly affect the metabolic phenotypes of the host. Although many studies have described the apparent effects of gut microbiota on human health, the development of metagenomics and culturomics in the past decade has generated a large amount of evidence suggesting a causal relationship between gut microbiota and obesity. The interaction between the gut microbiota and host is realized by microbial metabolites with multiple biological functions. We concentrated here on several representative beneficial species connected with obesity as well as the mechanisms, with particular emphasis on microbiota-dependent metabolites. Finally, we consider the potential clinical significance of these relationships to fuel the conception and realization of novel therapeutic and preventive strategies.
资助项目	Science and Technology Program of Yantai[2020MSGY076] ; Youth Innovation Promotion Association of the Chinese Academy of Sciences[2018246]
WOS关键词	VISCERAL FAT ACCUMULATION ; DIET-INDUCED OBESITY ; CHAIN AMINO-ACIDS ; LACTIS CECT 8145 ; BODY-MASS INDEX ; INSULIN-RESISTANCE ; BIFIDOBACTERIUM-ANIMALIS ; LACTOBACILLUS-REUTERI ; AKKERMANSIA-MUCINIPHILA ; INTESTINAL MICROBIOTA
WOS研究方向	Endocrinology & Metabolism
语种	英语
WOS记录号	WOS:000693844400001
资助机构	Science and Technology Program of Yantai ; Youth Innovation Promotion Association of the Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/29746]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
通讯作者	Song, Yipeng; Qin, Song
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 2.Yantai Univ, Coll Life Sci, Yantai, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 4.Chinese Acad Sci, Shenzhen Inst Adv Technol, Ctr Energy Metab & Reprod, Shenzhen Key Lab Metab Hlth, Shenzhen, Peoples R China 5.Yantai Yuhuangding Hosp, Dept Radiotherapy, Yantai, Peoples R China
推荐引用方式 GB/T 7714	Li, Lili,Zhang, Yubing,Speakman, John Roger,et al. The gut microbiota and its products: Establishing causal relationships with obesity related outcomes[J]. OBESITY REVIEWS,2021:14.
APA	Li, Lili,Zhang, Yubing,Speakman, John Roger,Hu, Shanliang,Song, Yipeng,&Qin, Song.(2021).The gut microbiota and its products: Establishing causal relationships with obesity related outcomes.OBESITY REVIEWS,14.
MLA	Li, Lili,et al."The gut microbiota and its products: Establishing causal relationships with obesity related outcomes".OBESITY REVIEWS (2021):14.