Effects of the Laplace pressure on the cells during cytokinesis

doi:10.1016/j.isci.2021.102945

CORC > 力学研究所 > 中国科学院力学研究所 > 非线性力学国家重点实验室

	Effects of the Laplace pressure on the cells during cytokinesis
	Wang XH(王小环)2,3,4; Li L(李龙)3,4; Shao YF(邵颖峰)3,4; Wei JC(韦佳辰)3,4; Song, Ruopu 1; Zheng SJ(郑松杰)2,3,4; Li YQ(李俞桥)2,3,4; Song F(宋凡)2,3,4
刊名	ISCIENCE
	2021-09-24
卷号	24 期号:9 页码:17
DOI	10.1016/j.isci.2021.102945
通讯作者	Song, Fan(songf@lnm.imech.ac.cn)
英文摘要	The Laplace pressure is one of the most fundamental regulators that determine cell shape and function, and thus has been receiving widespread attention. Here, we systemically investigate the effect of the Laplace pressure on the shape and function of the cells during cytokinesis. We find that the Laplace pressure during cytokinesis can directly control the distribution and size of cell blebbing and adjust the symmetry of cell division by virtue of changing the characteristics of cell blebbing. Further, we demonstrate that the Laplace pressure changes the structural uniformity of cell boundary to regulate the symmetry of cell division. Our findings provide further insights as to the important role of the Laplace pressure in regulating the symmetry of cell division during cytokinesis.
分类号	二类/Q1
资助项目	National Natural Science Foundation of China[11972041] ; National Natural Science Foundation of China[11902327] ; Youth Innovation Promotion Association CAS ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB22040102]
WOS关键词	INTRACELLULAR PRESSURE ; SPINDLE ORIENTATION ; MEMBRANE ; POSITION ; TENSION ; SURFACE ; BLEBS ; SIZE ; PROLIFERATION ; CONTRACTILE
WOS研究方向	Science & Technology - Other Topics
语种	英语
WOS记录号	WOS:000698069100011
资助机构	National Natural Science Foundation of China ; Youth Innovation Promotion Association CAS ; Strategic Priority Research Program of the Chinese Academy of Sciences
其他责任者	Song, Fan
内容类型	期刊论文
源URL	[http://dspace.imech.ac.cn/handle/311007/87507]
专题	力学研究所_非线性力学国家重点实验室
作者单位	1.Northeastern Univ, Sch Life Sci & Hlth, Shenyang 110169, Peoples R China 2.Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China; 3.Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beijing 100190, Peoples R China; 4.Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China;
推荐引用方式 GB/T 7714	Wang XH,Li L,Shao YF,et al. Effects of the Laplace pressure on the cells during cytokinesis[J]. ISCIENCE,2021,24(9):17.
APA	王小环.,李龙.,邵颖峰.,韦佳辰.,Song, Ruopu.,...&宋凡.(2021).Effects of the Laplace pressure on the cells during cytokinesis.ISCIENCE,24(9),17.
MLA	王小环,et al."Effects of the Laplace pressure on the cells during cytokinesis".ISCIENCE 24.9(2021):17.