Immune response and energy metabolism of Chlamys farreri under Vibrio anguillarum challenge and high temperature exposure

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	Immune response and energy metabolism of Chlamys farreri under Vibrio anguillarum challenge and high temperature exposure
	Wang, Xingqiang 1,2; Wang, Lingling 1; Zhang, Huan 1; Ji, Qingzhi 1; Song, Linsheng 1; Qiu, Limei 1; Zhou, Zhi 1; Wang, Mengqiang1 ; Wang, Leilei 1
刊名	FISH & SHELLFISH IMMUNOLOGY
	2012-10-01
卷号	33 期号:4 页码:1016-1026
关键词	Immune response Energy metabolism Chlamys farreri Vibrio anguillarum High temperature
ISSN号	1050-4648
通讯作者	Song, LS (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
英文摘要	The complex interactions among host, pathogen and environment are believed to be the main causes for the mass mortality of cultured scallops during summer period. In the present study, the temporal variations of immune and energy parameters of Chlamys farreri under Vibrio anguillarum challenge, higher temperature (29 degrees C) exposure as well as their combined treatment were investigated in order to better understand the energetic mechanisms of scallop immune defense. After the treatments, the superoxide anion level, the activities of superoxide dismutase (SOD) and acid phosphatase, as well as heat shock protein 70 expression level in the hemolymph of scallops increased substantially within 48 h. And as time progressed, the malondialdehyde content in the serum of scallops in the higher temperature treated and the combined stress treated groups were significantly increased, while the SOD activity was significantly depressed (96 h, P < 0.05). After 3 h, a significant decline (P < 0.05) in glycogen reserves was observed in the examined tissues of all the scallops in the bacteria challenged, higher temperature treated and the combined stress treated groups. The cellular energy allocation (CEA) in the examined tissues dropped considerably when the treatments lasted 48 h. There was a significant decline in the CEA and a significant increase in the energy consumption in the examined tissues compared with other treatments when the scallops were exposed to the combined stress for 96 h (P < 0.05). All the results demonstrated that the antioxidant systems and acute phase response system in scallops were not enough to wholly repair oxidative damage caused by higher temperature and the combined stress with bacteria challenge, and glycogen reserved in relative tissues were mobilized to meet the increased energy demands during the process of immune defense. Immune defense against the combined stress imposed greater costs on scallop's energy expenditure than either stressor alone, and CEA could be a useful tool to evaluate energetic allocation. The information provided valuable insights into possible mechanisms of scallop mass mortalities during summer period. (C) 2012 Elsevier Ltd. All rights reserved.
学科主题	Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences
收录类别	SCI
原文出处	10.1016/j.fsi.2012.08.026
语种	英语
WOS记录号	WOS:000310185800040
公开日期	2013-09-24
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/12351]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Huaihai Inst Technol, Jiangsu Key Lab Marine Biotechnol, Lianyungang 222005, Peoples R China
推荐引用方式 GB/T 7714	Wang, Xingqiang,Wang, Lingling,Zhang, Huan,et al. Immune response and energy metabolism of Chlamys farreri under Vibrio anguillarum challenge and high temperature exposure[J]. FISH & SHELLFISH IMMUNOLOGY,2012,33(4):1016-1026.
APA	Wang, Xingqiang.,Wang, Lingling.,Zhang, Huan.,Ji, Qingzhi.,Song, Linsheng.,...&Wang, Leilei.(2012).Immune response and energy metabolism of Chlamys farreri under Vibrio anguillarum challenge and high temperature exposure.FISH & SHELLFISH IMMUNOLOGY,33(4),1016-1026.
MLA	Wang, Xingqiang,et al."Immune response and energy metabolism of Chlamys farreri under Vibrio anguillarum challenge and high temperature exposure".FISH & SHELLFISH IMMUNOLOGY 33.4(2012):1016-1026.