Ultrasonic identification and regression analysis of 294 thyroid follicular tumors

doi:10.4103/jcrt.JCRT_913_19

	Ultrasonic identification and regression analysis of 294 thyroid follicular tumors
	Ou, Di 1,2; Yao, Jincao 1,2; Jin, Ju 2,3; Yan, Meiying 1,2; Shi, Kaiyuan 1,2; Zheng, Qiuqing 1,2; Yang, Chen 1,2; Xu, Dong 1,2
刊名	JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
	2020-09-01
卷号	16
关键词	Follicular thyroid adenoma follicular thyroid carcinoma ultrasound signal
ISSN号	0973-1482
DOI	10.4103/jcrt.JCRT_913_19
通讯作者	Yang, Chen(yangchen@zjcc.org.cn) ; Xu, Dong(xudong@zjcc.org.cn)
英文摘要	Context: We analyzed the clinical features and ultrasound image features of follicular thyroid carcinoma (FTC) and follicular thyroid adenoma (FTA). Aims: This study aimed to identify ultrasonographic differences and correlations between FTC and FTA. Meanwhile, ultrasonographic manifestations of thyroid follicular tumor were also retrospectively analyzed. Settings and Design: Using pathological results as the gold standard, the clinical and ultrasonic image characteristics of FTA and FTC were statistically analyzed, and the differences were analyzed. Materials and Methods: A total of 304 patients who were diagnosed with FTC or FTA by pathology after thyroidectomy from March 2009 to March 2018 were enrolled in this study. Their ultrasonic images were analyzed; image features were extracted and correlation analyses for these features were conducted. Differences in ultrasonic images between FTC and FTA were also compared. Statistical Analysis Used: Independent sample t-test; Wilcoxon rank sum test; A Chi-square test: Univariate and multivariate logistic regression analyses. Results: When performing ultrasound diagnosis, attention should be paid to identify FTC and FTA in terms of age, nodular goiter conditions, nodular boundary conditions, internal echo, calcification, blood flow signals, thyroid imaging reporting and data system (TI-RADS) grading and cystic solidity conditions. Moreover, a multivariate logistic regression showed that the boundaries were unclear, and cystic degeneration, TI-RADS, hypoecho, nodular goiter, macrocalcification and microcalcification were associated with FTC. Among them, macrocalcification is a protective factor for thyroid follicular tumors, and other indicators are risk factors. Conclusion: Ultrasound can provide valuable information for the identification of follicular neoplasms, but further research in this area is still necessary.
资助项目	National Natural Science Foundation of China[81871370] ; Zhejiang Provincial Natural Science Foundation of China[LSD19H180001]
WOS关键词	CARCINOMA ; PAPILLARY ; NODULES ; MICROCARCINOMA ; PREDICTION ; MALIGNANCY ; DIAGNOSIS ; ABLATION ; BENIGN ; CANCER
WOS研究方向	Oncology
语种	英语
出版者	WOLTERS KLUWER MEDKNOW PUBLICATIONS
WOS记录号	WOS:000577107800014
资助机构	National Natural Science Foundation of China ; Zhejiang Provincial Natural Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/104567]
专题	中国科学院合肥物质科学研究院
通讯作者	Yang, Chen; Xu, Dong
作者单位	1.Univ Chinese Acad Sci, Zhejiang Canc Hosp, Canc Hosp, Dept Ultrasound, Hangzhou 310022, Peoples R China 2.Chinese Acad Sci, Inst Canc & Basic Med IBMC, Hangzhou 310022, Peoples R China 3.Univ Chinese Acad Sci, Zhejiang Canc Hosp, Canc Hosp, Dept Pathol, Hangzhou, Peoples R China
推荐引用方式 GB/T 7714	Ou, Di,Yao, Jincao,Jin, Ju,et al. Ultrasonic identification and regression analysis of 294 thyroid follicular tumors[J]. JOURNAL OF CANCER RESEARCH AND THERAPEUTICS,2020,16.
APA	Ou, Di.,Yao, Jincao.,Jin, Ju.,Yan, Meiying.,Shi, Kaiyuan.,...&Xu, Dong.(2020).Ultrasonic identification and regression analysis of 294 thyroid follicular tumors.JOURNAL OF CANCER RESEARCH AND THERAPEUTICS,16.
MLA	Ou, Di,et al."Ultrasonic identification and regression analysis of 294 thyroid follicular tumors".JOURNAL OF CANCER RESEARCH AND THERAPEUTICS 16(2020).