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	Biomarker responses in the bivalve (chlamys farreri) to exposure of the environmentally relevant concentrations of lead, mercury, copper
	Zhang, Ying1; Song, Jinming; Yuan, Huamao; Xu, Yayan1; He, Zhipeng2; Duan, Liqin1
刊名	Environmental toxicology and pharmacology
	2010-07-01
卷号	30期号:1页码:19-25
关键词	Heavy metal Antioxidant enzyme Cyp450 Biomarker Bivalve
ISSN号	1382-6689
DOI	10.1016/j.etap.2010.03.008
英文摘要	Water samples collected from bohai bay were determined to describe the distributions of lead, mercury, and copper in this area, indicating that mean values of the three metals were 1.63 mu g/l, 4.85 x 10(-2) mu g/l, and 2.68 mu g/l, respectively. only lead exceeded the first class limit of seawater quality standard in china. then, antioxidant enzymes, lipid peroxidation, and metabolic enzymes were investigated in bivalves (chlamys farreri), exposed to three metals at the environmental concentration levels obtained from our investigation. significantly reduced sod, cat and gpx activities, in lead-exposed group were observed and resulted in obvious lipid peroxidation. in contrast, mercury and copper did not show such clear oxidative stresses. in consistent with the oxidative stress variations, exposed only to lead caused a great inhibition on erod activity. multi-biomarker responses in bivalve when exposed to lead at the environmentally relevant concentration in bohai bay suggested that lead may possess a potential risk in this area. (c) 2010 elsevier b.v. all rights reserved.
WOS关键词	RAT-BRAIN REGIONS ; OXIDATIVE STRESS ; ANTIOXIDANT DEFENSE ; GENE-EXPRESSION ; HEAVY-METALS ; INDUCTION ; TOXICITY ; ENZYMES ; FISH ; SYSTEM
WOS研究方向	Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology
WOS类目	Environmental Sciences ; Pharmacology & Pharmacy ; Toxicology
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000279089000004
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2414766
专题	中国科学院大学
作者单位	1.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 2.Fishery Design Inst Shandong Prov, Jinan 250013, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Ying,Song, Jinming,Yuan, Huamao,et al. Biomarker responses in the bivalve (chlamys farreri) to exposure of the environmentally relevant concentrations of lead, mercury, copper[J]. Environmental toxicology and pharmacology,2010,30(1):19-25.
APA	Zhang, Ying,Song, Jinming,Yuan, Huamao,Xu, Yayan,He, Zhipeng,&Duan, Liqin.(2010).Biomarker responses in the bivalve (chlamys farreri) to exposure of the environmentally relevant concentrations of lead, mercury, copper.Environmental toxicology and pharmacology,30(1),19-25.
MLA	Zhang, Ying,et al."Biomarker responses in the bivalve (chlamys farreri) to exposure of the environmentally relevant concentrations of lead, mercury, copper".Environmental toxicology and pharmacology 30.1(2010):19-25.

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