Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from North American ginseng
Yu, Xiaona1,2; Yang, Xiushi1,3; Cui, Bo2; Wang, Lijun1,4; Ren, Guixing1
刊名INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
2014
卷号65页码:357-361
关键词North American ginseng Alkali-extractable polysaccharide Bioactivity
ISSN号0141-8130
DOI10.1016/j.ijbiomac.2014.01.046
通讯作者Yu, Xiaona
英文摘要The alkali-extractable polysaccharide (AEP) was isolated from the root of North American ginseng. Two fractions, AEP-1 and AEP-2, were further purified by gel filtration column chromatography. Gas chromatography analysis identified that AEP-1 was composed of Glc, Gal and GalA. And AEP-2 mainly contained Ara, Man, Gal, Glc and GalA. Antioxidant assays indicated that AEP and AEP-2 exhibited significant antioxidant activities in a dose-dependent manner. AEP-2 also exhibited macrophage-activating activity by increasing NO, TNF-alpha and IL-6 production. The results suggest that AEP-2 could be used as potential antioxidants and immunomodulators. (c) 2014 Elsevier B.V. All rights reserved.
学科主题Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science ; BIOCHEMISTRY & MOLECULAR BIOLOGY
语种英语
出版者ELSEVIER SCIENCE BV
WOS记录号WOS:000334092900048
内容类型期刊论文
源URL[http://111.203.20.206/handle/2HMLN22E/4915]  
专题作物科学研究所_种质资源保存与研究中心
作者单位1.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China
2.Qilu Univ Technol, Sch Food & Bioengn, Jinan 250353, Peoples R China
3.Shanxi Univ, Res Ctr Environm Sci & Engn, Taiyuan 030006, Peoples R China
4.Chinese Univ Hong Kong, Sch Life Sci, Shatin, Hong Kong, Peoples R China
推荐引用方式
GB/T 7714
Yu, Xiaona,Yang, Xiushi,Cui, Bo,et al. Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from North American ginseng[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2014,65:357-361.
APA Yu, Xiaona,Yang, Xiushi,Cui, Bo,Wang, Lijun,&Ren, Guixing.(2014).Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from North American ginseng.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,65,357-361.
MLA Yu, Xiaona,et al."Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from North American ginseng".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 65(2014):357-361.
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