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	Solid-phase synthesis for novel nerve agent adducted nonapeptides as biomarkers
	Li, Xinhai1,2; Yuan, Ling1,2; Wang, Qinggang3; Liang, Longhui1,2; Huang, Guilan1,2; Li, Xiaosen1,2; Zhang, Chunhong1,2; Liu, Shilei1,2; Liu, Jingquan1,2
刊名	TETRAHEDRON LETTERS
	2017-04-12
卷号	58期号:15页码:1437-1440
关键词	D-5-VX D-15-GD Nonapeptide Solid-phase BuChE-OPNA biomarkers
英文摘要	An efficient synthesis of d(5)-VX adducted nonapeptide and d(15)-GD adducted nonapeptide via solid-phase approach has been developed. The deuterated peptides could be used as the isotope-labeled internal standard for LC-MS/MS detecting the BuChE-OPNA biomarkers. This method also offers an access to the synthesis and detection of other phosphorylated nonapeptides. (C) 2017 Elsevier Ltd. All rights reserved.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Organic
研究领域[WOS]	Chemistry
关键词[WOS]	TANDEM MASS-SPECTROMETRY ; CHEMICAL WARFARE AGENTS ; DEGRADATION-PRODUCTS ; SARIN ; SAMPLES ; ACID ; IONIZATION ; EXPOSURE
收录类别	SCI
语种	英语
WOS记录号	WOS:000399517600003
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/9285]
专题	青岛生物能源与过程研究所_材料生物技术研究中心
作者单位	1.State Key Lab NBC Protect Civilian, Beijing 102205, Peoples R China 2.Res Inst Chem Def, Lab Analyt Chem, Beijing 102205, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biobased Mat, 189 Songling Rd, Qingdao 266101, Peoples R China
推荐引用方式 GB/T 7714	Li, Xinhai,Yuan, Ling,Wang, Qinggang,et al. Solid-phase synthesis for novel nerve agent adducted nonapeptides as biomarkers[J]. TETRAHEDRON LETTERS,2017,58(15):1437-1440.
APA	Li, Xinhai.,Yuan, Ling.,Wang, Qinggang.,Liang, Longhui.,Huang, Guilan.,...&Liu, Jingquan.(2017).Solid-phase synthesis for novel nerve agent adducted nonapeptides as biomarkers.TETRAHEDRON LETTERS,58(15),1437-1440.
MLA	Li, Xinhai,et al."Solid-phase synthesis for novel nerve agent adducted nonapeptides as biomarkers".TETRAHEDRON LETTERS 58.15(2017):1437-1440.

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