Medical application of microbial biopolyesters polyhydroxyalkanoates | |
Qiong Wu ; Yang Wang ; Guo-Qiang Chen | |
2010-10-12 ; 2010-10-12 | |
关键词 | Application Bibliography Practical/ biodegradable materials biomedical materials drugs microorganisms polymer blends prosthetics tissue engineering/ microbial biopolyester polyhydroxyalkanoate microorganism 3-hydroxybutyrate copolymer 3-hydroxyvalerate poly-4-hydroxybutyrate tissue engineering medical applications biocompatibility biodegradability medical devices development tissue repair artificial organ construction drug delivery PHA blend/ A8770M Biomedical materials A8770G Patient care and treatment |
中文摘要 | Polyhydroxyalkanoates (PHA) are a family of polyesters synthesized by microorganisms under unbalanced growth conditions. PHA including poly-3-hydroxybutyrate (PHB), copolymers of 3-hydroxybutyrate and 3-hydroxyvalerate (PHBV), poly-4-hydroxybutyrate (P4HB), copolymers of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx), and poly-3-hydroxyoctanoate (PHO) are now available in sufficient quantity for tissue engineering medical application studies due to their reasonable biocompatibility, adjustable mechanical properties, and controllable biodegradability. This paper reviews many achievements based on PHA for medical devices development, tissue repair, artificial organ construction, drug delivery, and nutritional/therapeutic uses. Combined with the recent FDA approval for P4HB clinical application, one can expect a good prospect for PHA application in the medical fields. |
语种 | 英语 |
出版者 | Marcel Dekker Inc. ; USA |
内容类型 | 期刊论文 |
源URL | [http://hdl.handle.net/123456789/81778] |
专题 | 清华大学 |
推荐引用方式 GB/T 7714 | Qiong Wu,Yang Wang,Guo-Qiang Chen. Medical application of microbial biopolyesters polyhydroxyalkanoates[J],2010, 2010. |
APA | Qiong Wu,Yang Wang,&Guo-Qiang Chen.(2010).Medical application of microbial biopolyesters polyhydroxyalkanoates.. |
MLA | Qiong Wu,et al."Medical application of microbial biopolyesters polyhydroxyalkanoates".(2010). |
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